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用氨基酸制备和表征金纳米颗粒及其稳定性研究

Preparation and characterization of gold nanoparticles with amino acids, examination of their stability.

作者信息

Zarabi Maryam Farahnak, Arshadi Nematollah, Farhangi Ali, Akbarzadeh Azim

机构信息

Department of Chemistry, Faculty of Sciences, Zanjan University, Zanjan, Islamic Republic of Iran ; Department of Pilot Nanobiotechnology, Pasteur Institute of Iran, Tehran, Islamic Republic of Iran.

Department of Chemistry, Faculty of Sciences, Zanjan University, Zanjan, Islamic Republic of Iran.

出版信息

Indian J Clin Biochem. 2014 Jul;29(3):306-14. doi: 10.1007/s12291-013-0358-4. Epub 2013 Jul 23.

DOI:10.1007/s12291-013-0358-4
PMID:24966478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4062661/
Abstract

We report a novel strategy for the synthesis and capping of gold nanoparticles (GNPs) by tryptophan, glutamic acid and aspartic acid. The ratio of chloroaurate ions to amino acid was optimized in the reaction medium to obtain monodispersed GNPs. The size of nanoparticles and size distribution were controlled by sodium dodecyl sulfate which demonstrated high stability in aqueous solution over a period of time. GNPs were characterized by UV-Vis spectroscopy, dynamic light scattering and transmission electron microscopy.

摘要

我们报道了一种通过色氨酸、谷氨酸和天冬氨酸合成及包覆金纳米颗粒(GNPs)的新策略。在反应介质中优化了氯金酸根离子与氨基酸的比例,以获得单分散的GNPs。通过十二烷基硫酸钠控制纳米颗粒的尺寸和尺寸分布,其在水溶液中一段时间内表现出高稳定性。通过紫外可见光谱、动态光散射和透射电子显微镜对GNPs进行了表征。

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