Kapadia Naaz M, Bagher Shaghayegh, Popovic Milos R
J Spinal Cord Med. 2014 Nov;37(6):734-43. doi: 10.1179/2045772314Y.0000000203. Epub 2014 Jun 26.
The primary objective was to compare the benefits of single (COT1) versus double (COT2) dose of conventional occupational therapy (COT) in improving voluntary hand function in individuals with incomplete, sub-acute C3-C7 spinal cord injury (SCI). The secondary objective was to compare these two interventions versus functional electrical stimulation therapy plus COT (FES + COT).
Retrospective analysis. Setting Inpatient spinal cord rehabilitation center, Toronto.
Individuals with traumatic incomplete sub-acute SCI.
Data from Phases I and II (ClinicalTrials.gov ID NCT00221117) randomized control trials were pooled together for the purpose of this study. Participants in the COT1 group received 45 hours of therapy, the COT2 group received 80 hours of therapy, and the FES + COT group received 40 hours of COT therapy +40 hours of FES therapy.
We analyzed the functional independence measure (FIM) and the spinal cord independence measure (SCIM) self-care sub-scores. Results The mean change scores on the FIM self-care sub-score for the COT1, COT2, and FES + COT groups were 12.8, 10, and 20.1 points, respectively. Similarly, the mean change scores on the SCIM self-care sub-score for the COT1, COT2, and FES + COT groups were, 2.6, 3.16, and 10.2 points, respectively.
Increased rehabilitation intensity alone may not always be beneficial. The type of intervention plays a significant role in determining functional changes. In this instance, receiving one (COT1) or two (COT2) doses of COT resulted in similar outcomes, however, FES + COT therapy yielded much better outcomes compared to COT1 and COT2 interventions.
主要目的是比较单次剂量(COT1)与双次剂量(COT2)的传统职业疗法(COT)对改善不完全性、亚急性C3 - C7脊髓损伤(SCI)患者的自主手部功能的益处。次要目的是比较这两种干预措施与功能性电刺激疗法加COT(FES + COT)的效果。
回顾性分析。地点:多伦多的住院脊髓康复中心。
创伤性不完全性亚急性SCI患者。
为了本研究,将来自I期和II期(ClinicalTrials.gov标识符NCT00221117)随机对照试验的数据汇总在一起。COT1组的参与者接受45小时的治疗,COT2组接受80小时的治疗,FES + COT组接受40小时的COT治疗 + 40小时的FES治疗。
我们分析了功能独立性测量(FIM)和脊髓独立性测量(SCIM)自理子评分。结果:COT1组、COT2组和FES + COT组在FIM自理子评分上的平均变化分数分别为12.8分、10分和20.1分。同样,COT1组、COT2组和FES + COT组在SCIM自理子评分上的平均变化分数分别为2.6分、3.16分和10.2分。
仅增加康复强度不一定总是有益的。干预类型在决定功能变化方面起着重要作用。在这种情况下,接受单次(COT1)或两次(COT2)剂量的COT产生了相似的结果,然而,与COT1和COT2干预相比,FES + COT疗法产生了更好的结果。