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一种可植入式眼压传感器:初始安全性结果

An implantable intraocular pressure transducer: initial safety outcomes.

作者信息

Melki Samir, Todani Amit, Cherfan George

机构信息

Boston Eye Group, Brookline, Massachusetts2Beirut Eye Specialist Hospital, Beirut, Lebanon.

Department of Ophthalmology, Albany Medical Center, Albany, New York.

出版信息

JAMA Ophthalmol. 2014 Oct;132(10):1221-5. doi: 10.1001/jamaophthalmol.2014.1739.

DOI:10.1001/jamaophthalmol.2014.1739
PMID:24970583
Abstract

IMPORTANCE

To our knowledge, this is a report of the first implantation of a wireless intraocular pressure transducer (WIT) in a human eye.

OBJECTIVE

To report preliminary safety data on the WIT.

DESIGN, SETTING, AND PARTICIPANT: In an institutional setting, a patient with open-angle glaucoma consented to be the recipient of the WIT in one eye in an interventional study design.

INTERVENTIONS

The WIT was implanted into the ciliary sulcus following extracapsular cataract extraction and "in the bag" intraocular lens implantation. The patient was monitored postoperatively for 18 months.

MAIN OUTCOMES AND MEASURES

Any adverse events.

RESULTS

There were no complications noted during the WIT insertion or postoperatively. No persistent intraocular inflammation, pigment dispersion, or angle narrowing was noted.

CONCLUSIONS AND RELEVANCE

The WIT was well tolerated in the eye and no overt signs of toxicity or other adverse events were noted. This may allow the constant monitoring of intraocular pressure in the future.

摘要

重要性

据我们所知,这是关于无线眼压传感器(WIT)首次植入人眼的报告。

目的

报告WIT的初步安全性数据。

设计、地点和参与者:在一个机构环境中,一名开角型青光眼患者在一项介入性研究设计中同意接受一只眼睛植入WIT。

干预措施

在白内障囊外摘除和“囊袋内”人工晶状体植入后,将WIT植入睫状沟。术后对患者进行了18个月的监测。

主要结局和测量指标

任何不良事件。

结果

在WIT植入过程中或术后均未发现并发症。未观察到持续性眼内炎症、色素播散或房角变窄。

结论和意义

WIT在眼中耐受性良好,未观察到明显的毒性迹象或其他不良事件。这可能使未来能够持续监测眼压。

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