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磁化水对小鼠卵巢、植入前阶段子宫内膜及输卵管上皮细胞的影响。

Effects of magnetized water on ovary, pre-implantation stage endometrial and fallopian tube epithelial cells in mice.

作者信息

Hafizi Leili, Gholizadeh Mostafa, Karimi Mohammad, Hosseini Golkoo, Mostafavi-Toroghi Hesam, Haddadi Mehdi, Rezaiean Amin, Ebrahimi Mahmoud, Emami Meibodi Neda

机构信息

Department of Obstetrics and Gynecology, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Chemistry, Faculty of Basic Sciences, Ferdowsi University, Mashhad, Iran.

出版信息

Iran J Reprod Med. 2014 Apr;12(4):243-8.

Abstract

BACKGROUND

Magnetized water has made many improvements in industry, agriculture and medicine. However its utilization in medicine still remains controversial.

OBJECTIVE

In this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice.

MATERIALS AND METHODS

Eighty female NRMI mice were recruited to this experimental study and randomly divided into two groups: the control group which drank normal water and the experimental (case) group which drank magnetized water for 2 weeks. Super-ovulation was induced in these mice and then they were mated with male mice as well. Samples of ovary, uterus and fallopian tube were obtained at the pre-implantation stage. Then, after preparation, the number of corpus lutea in each ovary was counted and the height of fallopian and endometrial epithelial cells was measured by light microscopy.

RESULTS

Data analysis showed a significant increase in the mean number of corpus lutea and the height of epithelial cells in fallopian tube comparing the case with the control group (p=0.01, p=0.002 respectively) whereas uterus epithelial cells of the case group showed insignificant increase in height, in compare with the control group (p=0.052).

CONCLUSION

Our results suggest that magnetized water intake increases the number of corpus lutea and the height of fallopian tube epithelial cells. Further research is needed to determine whether this will increase in the success rate of fertility.

摘要

背景

磁化水在工业、农业和医学领域有诸多改善。然而其在医学中的应用仍存在争议。

目的

本研究旨在探讨磁化水对雌性小鼠植入前阶段子宫内膜和输卵管上皮细胞高度以及黄体数量的影响。

材料与方法

80只雌性NRMI小鼠被纳入本实验研究,并随机分为两组:饮用普通水的对照组和饮用磁化水2周的实验(病例)组。对这些小鼠进行超排卵诱导,然后使其与雄性小鼠交配。在植入前阶段获取卵巢、子宫和输卵管样本。随后,样本制备完成后,计数每个卵巢中的黄体数量,并通过光学显微镜测量输卵管和子宫内膜上皮细胞的高度。

结果

数据分析显示,与对照组相比,病例组的黄体平均数量和输卵管上皮细胞高度显著增加(分别为p = 0.01,p = 0.002),而病例组子宫上皮细胞高度与对照组相比虽有增加,但差异不显著(p = 0.052)。

结论

我们的结果表明,摄入磁化水可增加黄体数量和输卵管上皮细胞高度。是否会提高生育成功率还需进一步研究确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4332/4071628/df53db3b0db5/ijrm-12-243-g001.jpg

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