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Circulating CYFRA 21-1 is a Specific Diagnostic and Prognostic Biomarker in Biliary Tract Cancer.循环细胞角蛋白19片段(CYFRA 21-1)是胆管癌的一种特异性诊断和预后生物标志物。
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Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos.中泰老毗邻地区华支睾吸虫病与华支睾吸虫相关性胆管癌
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老挝人民民主共和国 2009-2011 年华支睾吸虫和微小肠吸虫感染的危险因素。

Risk factors for Opisthorchis viverrini and minute intestinal fluke infections in Lao PDR, 2009-2011.

机构信息

Department of Infectious Diseases, College of Medicine, Eulji University, Daejeon, Korea; Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea; Department of Parasitology and Medical Research Institute, School of Medicine, Chungbuk National University, Cheongju, Korea; Department of Environmental Medical Biology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea; Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul, Korea; Department of Microbiology, College of Medicine, Eulji University, Daejeon, Korea; Department of Parasitology, Korea University School of Medicine, Seoul, Korea; Department of Parasitology and Institute of Health Sciences, Gyeongsang National University, School of Medicine, Jinju, Korea; Department of Communicable Disease Control, Ministry of Health, Vientiane, Lao PDR.

Department of Infectious Diseases, College of Medicine, Eulji University, Daejeon, Korea; Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea; Department of Parasitology and Medical Research Institute, School of Medicine, Chungbuk National University, Cheongju, Korea; Department of Environmental Medical Biology and Institute of Tropical Medicine, Yonsei University College of Medicine, Seoul, Korea; Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul, Korea; Department of Microbiology, College of Medicine, Eulji University, Daejeon, Korea; Department of Parasitology, Korea University School of Medicine, Seoul, Korea; Department of Parasitology and Institute of Health Sciences, Gyeongsang National University, School of Medicine, Jinju, Korea; Department of Communicable Disease Control, Ministry of Health, Vientiane, Lao PDR

出版信息

Am J Trop Med Hyg. 2014 Aug;91(2):384-8. doi: 10.4269/ajtmh.13-0596. Epub 2014 Jun 30.

DOI:10.4269/ajtmh.13-0596
PMID:24980495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4125266/
Abstract

The purpose of this report is to compare the prevalence of Opisthorchis viverrini/minute intestinal fluke (Ov/MIF) in Lao People's Democratic Republic according to different regions and evaluate the effect of ingestion of raw freshwater fish on the infection. Demographic data, behavioral data, and symptoms were obtained, and the Kato-Katz method was used for the diagnosis of Ov/MIF. In total, 3,046 individuals were enrolled. The risk factors associated with acquisition of Ov/MIF were raw fish consumption and province. Khong Island showed the highest prevalence (odds ratio = 80.1, 95% confidence interval = 47.9-133.9, P < 0.001) compared with other districts, and raw fish consumption was related to Ov/MIF infection. Administration of praziquantel to entire populations, education (avoiding consumption of raw food dishes and improved hygiene), and access to clean water and sanitation should be considered.

摘要

本报告的目的是比较老挝人民民主共和国不同地区肝片形吸虫/肠微小型吸虫(Ov/MIF)的流行情况,并评估生食淡水鱼对感染的影响。收集人口统计学数据、行为数据和症状,并用加藤厚涂片法诊断 Ov/MIF。共纳入 3046 人。与获得 Ov/MIF 相关的风险因素是食用生鱼和省份。孔岛的感染率最高(优势比=80.1,95%置信区间=47.9-133.9,P<0.001),与其他地区相比,生食鱼与 Ov/MIF 感染有关。应考虑对全体人群进行吡喹酮治疗、教育(避免食用生食品和改善卫生)以及提供清洁水和卫生设施。