Murphy James G, Yurasek Ali M, Meshesha Lidia Z, Dennhardt Ashley A, MacKillop James, Skidmore Jessica R, Martens Matthew P
Department of Psychology, The University of Memphis, Memphis, Tennessee.
Department of Psychology, University of Georgia, Athens, Georgia.
J Stud Alcohol Drugs. 2014 Jul;75(4):653-63. doi: 10.15288/jsad.2014.75.653.
Behavioral economic demand curves measure alcohol consumption as a function of price and may capture clinically relevant individual differences in alcohol-reinforcing efficacy. This study used a novel, behavioral-economic, hypothetical demand-curve paradigm to examine the association between family history of alcohol misuse and individual differences in both alcohol demand and the relative sensitivity of alcohol demand to next-day responsibilities.
Participants were 207 college students (47% male, 68.5% White, 27.4% African American, Mage = 19.5 years) who reported at least one heavy drinking episode (5/4 or more drinks on one occasion for a man/woman) in the past month and completed two versions of an alcohol purchase task (APT) that assessed hypothetical alcohol consumption across 17 drink prices. In one APT (standard), students imagined they had no next-day responsibilities, and in the other, they imagined having a 10:00 a.m. test the next day.
A series of analyses of covariance indicated that participants with at least one biological parent or grandparent who had misused alcohol reported similar levels of alcohol demand on the standard APT but significantly less sensitivity to the next-day academic responsibility as measured by the percentage of reduction in demand intensity and breakpoint across the no-responsibility and next-day-test conditions.
These findings provide initial evidence that APTs might clarify one potential mechanism of risk conferred by family history. Young adult heavy drinkers with a family history of problematic drinking may be less sensitive to next-day responsibilities that might modulate drinking in drinkers without a family history of alcohol problems.
行为经济学需求曲线将酒精消费衡量为价格的函数,并可能捕捉到酒精强化效果方面临床上相关的个体差异。本研究采用一种新颖的、行为经济学的假设需求曲线范式,来检验酒精滥用家族史与酒精需求的个体差异以及酒精需求对次日责任的相对敏感性之间的关联。
参与者为207名大学生(47%为男性,68.5%为白人,27.4%为非裔美国人,平均年龄 = 19.5岁),他们报告在过去一个月中至少有一次酗酒事件(男性/女性一次饮用5杯/4杯或更多),并完成了两个版本的酒精购买任务(APT),该任务评估了17种酒价下的假设酒精消费量。在一个APT(标准)中,学生想象他们次日没有责任,而在另一个APT中,他们想象次日上午10点有一场考试。
一系列协方差分析表明,至少有一位亲生父母或祖父母曾滥用酒精的参与者在标准APT上报告的酒精需求水平相似,但在无责任和次日考试条件下,通过需求强度降低百分比和断点衡量,对次日学业责任的敏感性显著较低。
这些发现提供了初步证据,表明APT可能阐明家族史所赋予风险的一种潜在机制。有饮酒问题家族史的年轻成年酗酒者可能对次日责任不太敏感,而次日责任可能会调节无酒精问题家族史饮酒者的饮酒行为。