Lahti Jouni, Holstila Ansku, Lahelma Eero, Rahkonen Ossi
Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland.
PLoS One. 2014 Jul 2;9(7):e101548. doi: 10.1371/journal.pone.0101548. eCollection 2014.
Physical inactivity is a major public health problem associated with increased mortality risk. It is, however, poorly understood whether vigorous physical activity is more beneficial for reducing mortality risk than activities of lower intensity. The aim of this study was to examine associations of the intensity and volume of leisure-time physical activity with all-cause mortality among middle-aged women and men while considering sociodemographic and health related factors as covariates.
Questionnaire survey data collected in 2000-02 among 40-60-year-old employees of the City of Helsinki (N = 8960) were linked with register data on mortality (74% gave permission to the linkage) providing a mean follow-up time of 12-years. The analysis included 6429 respondents (79% women). The participants were classified into three groups according to intensity of physical activity: low moderate, high moderate and vigorous. The volume of physical activity was classified into three groups according to tertiles. Cox regression analysis was used to calculate hazard ratios (HR) and 95% confidence intervals (CIs) for all-cause mortality.
During the follow up 205 participants died. Leisure-time physical activity was associated with reduced risk of mortality. After adjusting for covariates the vigorous group (HR = 0.54, 95% CI 0.34-0.86) showed a reduced risk of mortality compared with the low moderate group whereas for the high moderate group the reductions in mortality risk (HR = 0.72, 95% CI 0.48-1.08) were less clear. Adjusting for the volume of physical activity did not affect the point estimates. Higher volume of leisure-time physical activity was also associated with reduced mortality risk; however, adjusting for the covariates and the intensity of physical activity explained the differences.
For healthy middle-aged women and men who engage in some physical activity vigorous exercise may provide further health benefits preventing premature deaths.
缺乏身体活动是一个主要的公共卫生问题，与死亡风险增加相关。然而，高强度身体活动在降低死亡风险方面是否比低强度活动更有益，目前尚不清楚。本研究的目的是在将社会人口学和健康相关因素作为协变量的情况下，研究中年女性和男性休闲时间身体活动的强度和量与全因死亡率之间的关联。
2000 - 2002年收集的赫尔辛基市40 - 60岁员工（N = 8960）的问卷调查数据与死亡率登记数据相关联（74%的人允许这种关联），平均随访时间为12年。分析纳入了6429名受访者（79%为女性）。参与者根据身体活动强度分为三组：低中等强度、高中等强度和高强度。身体活动量根据三分位数分为三组。采用Cox回归分析计算全因死亡率的风险比（HR）和95%置信区间（CI）。
随访期间205名参与者死亡。休闲时间身体活动与死亡风险降低相关。在调整协变量后，高强度组（HR = 0.54，95% CI 0.34 - 0.86）与低中等强度组相比，死亡风险降低，而高中等强度组死亡风险降低（HR = 0.72，95% CI 0.48 - 1.08）则不太明显。调整身体活动量不影响点估计值。较高的休闲时间身体活动量也与死亡风险降低相关；然而，调整协变量和身体活动强度解释了这些差异。
对于进行一定身体活动的健康中年女性和男性，高强度运动可能提供进一步的健康益处，预防过早死亡。
