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体力活动强度和类型对死亡率的影响:来自 Whitehall II 队列研究的结果。

Effect of intensity and type of physical activity on mortality: results from the Whitehall II cohort study.

机构信息

Centre for Research in Epidemiology & Population Health, INSERM, Villejuif, France.

出版信息

Am J Public Health. 2012 Apr;102(4):698-704. doi: 10.2105/AJPH.2011.300257. Epub 2011 Nov 28.

Abstract

OBJECTIVES

We examined the association of intensity and type of physical activity with mortality.

METHODS

We assessed the duration of physical activity by intensity level and type in 7456 men and women from the Whitehall II Study by questionnaire in 1997-1999 (mean ±SD age = 55.9 ± 6.0 years) and 5 years later. All-cause mortality was assessed until April 2009.

RESULTS

A total of 317 participants died during the mean follow-up of 9.6 years (SD = 2.7). Reporting at least 1 hour per week of moderate activity was associated with a 33% (95% confidence interval [CI] = 14%, 45%) lower risk of mortality compared with less than 1 hour. For all physical activity types examined, except housework, a duration of physical activity greater than 0 (≥ 3.5 hours for walking) was associated with lower mortality in age-adjusted analyses, but only the associations with sports (hazard ratio [HR] = 0.71; 95% CI = 0.56, 0.91) and do-it-yourself activity (HR = 0.68; 95% CI = 0.53, 0.98) remained in fully adjusted analyses.

CONCLUSIONS

It is important to consider both intensity and type of physical activity when examining associations with mortality.

摘要

目的

我们研究了身体活动强度和类型与死亡率之间的关系。

方法

我们通过问卷调查评估了 7456 名来自 Whitehall II 研究的男性和女性在 1997-1999 年(平均年龄±标准差为 55.9±6.0 岁)和 5 年后的身体活动持续时间、强度和类型。通过评估所有原因的死亡率,直至 2009 年 4 月。

结果

在平均 9.6 年(标准差=2.7)的随访期间,共有 317 名参与者死亡。与少于 1 小时相比,每周至少进行 1 小时中等强度的活动与死亡率降低 33%(95%置信区间为 14%,45%)相关。在所有检查的身体活动类型中,除家务外,在年龄调整分析中,身体活动时间大于 0(步行时间≥3.5 小时)与较低的死亡率相关,但只有与运动(风险比[HR]=0.71;95%置信区间为 0.56,0.91)和自己动手活动(HR=0.68;95%置信区间为 0.53,0.98)的关联在完全调整分析中仍然存在。

结论

在研究与死亡率的关联时,考虑身体活动的强度和类型很重要。

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