Onwulata C I, Rao D R, Vankineni P
Department of Food Science and Animal Industries, Alabama A&M University, Huntsville 35762.
Am J Clin Nutr. 1989 Jun;49(6):1233-7. doi: 10.1093/ajcn/49.6.1233.
The relative effectiveness of commercially available plain yogurt (Y), sweet acidophilus milk (SAM), hydrolyzed-lactose milk (HLM), a lactase tablet (LT), and whole milk (WM) was evaluated in 10 lactose-intolerant black subjects. In a 5 x 5 Latin square design, hourly breath hydrogen excretion (BHE) was measured for 5 h after the subjects consumed the above products (18 g lactose in each except HLM, which had 5 g). Mean BHE (ppm) for Y, SAM, LT, HLM, and WM were 12, 37, 29, 18, and 33, respectively. There was a significant (p less than 0.05) positive correlation of 0.808 between the symptoms reported and the mean peak BHE. However, the correlation between the symptoms and diagnosis by history was not significant. Although Y was as effective as HLM in minimizing lactose maldigestion, it was the least accepted by the subjects in sensory evaluations. Results of this study also indicate that microbial endogenous lactase in yogurt is superior to exogenous commercial lactase in alleviating lactose maldigestion.
在10名乳糖不耐受的黑人受试者中评估了市售原味酸奶（Y）、甜嗜酸乳杆菌奶（SAM）、水解乳糖奶（HLM）、乳糖酶片（LT）和全脂牛奶（WM）的相对有效性。采用5×5拉丁方设计，在受试者食用上述产品（除含5克乳糖的HLM外，每种产品含18克乳糖）后5小时测量每小时呼气氢排泄量（BHE）。Y、SAM、LT、HLM和WM的平均BHE（ppm）分别为12、37、29、18和33。报告的症状与平均峰值BHE之间存在显著（p<0.05）正相关，相关系数为0.808。然而，症状与病史诊断之间的相关性不显著。虽然Y在最小化乳糖消化不良方面与HLM一样有效，但在感官评价中它是受试者最不接受的。本研究结果还表明，酸奶中的微生物内源性乳糖酶在缓解乳糖消化不良方面优于外源性商业乳糖酶。
