Collett Brent R, Wehby George L, Barron Sheila, Romitti Paul A, Ansley Timothy N, Speltz Matthew L
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Department of Health Management and Policy, University of Iowa College of Public Health, University of Iowa, Iowa Testing Programs, Department of Epidemiology, University of Iowa College of Public Health, and Department of Psychology and Quantitative Foundations, University of Iowa
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Department of Health Management and Policy, University of Iowa College of Public Health, University of Iowa, Iowa Testing Programs, Department of Epidemiology, University of Iowa College of Public Health, and Department of Psychology and Quantitative Foundations, University of Iowa.
J Pediatr Psychol. 2014 Aug;39(7):743-51. doi: 10.1093/jpepsy/jsu049. Epub 2014 Jul 3.
To compare academic achievement in children with oral-facial clefts (OFC) with their unaffected siblings.
256 children with OFC were identified from the Iowa Registry for Congenital and Inherited Disorders, and 387 unaffected siblings were identified from birth certificates. These data were linked to Iowa Testing Programs achievement data. We compared academic achievement in children with OFC with their unaffected siblings using linear regression models, adjusted for potential confounders. In post hoc analyses, we explored modifiers of siblings' academic performance.
Achievement scores were similar between children with OFC and their siblings. Children with cleft palate only were significantly more likely to use special education than their unaffected siblings. Siblings' academic achievement was inversely related to distance in birth order and age from the affected child.
Children with OFC and their siblings received similar achievement scores. Younger siblings, in particular, may share a vulnerability to poor academic outcomes.
比较患有口腔面部裂隙（OFC）的儿童与其未受影响的兄弟姐妹的学业成绩。
从爱荷华州先天性和遗传性疾病登记处识别出256名患有OFC的儿童，并从出生证明中识别出387名未受影响的兄弟姐妹。这些数据与爱荷华州测试项目的成绩数据相关联。我们使用线性回归模型，对潜在混杂因素进行调整，比较了患有OFC的儿童与其未受影响的兄弟姐妹的学业成绩。在事后分析中，我们探讨了兄弟姐妹学业表现的调节因素。
患有OFC的儿童与其兄弟姐妹的成绩得分相似。仅患有腭裂的儿童比其未受影响的兄弟姐妹更有可能接受特殊教育。兄弟姐妹的学业成绩与出生顺序和与患病儿童的年龄差距呈负相关。
患有OFC的儿童与其兄弟姐妹的成绩得分相似。特别是年幼的兄弟姐妹，可能同样容易出现学业成绩不佳的情况。
