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巴西初级卫生保健对心脏和脑血管疾病死亡率的影响:基于纵向数据的全国性分析

Impact of primary health care on mortality from heart and cerebrovascular diseases in Brazil: a nationwide analysis of longitudinal data.

作者信息

Rasella Davide, Harhay Michael O, Pamponet Marina L, Aquino Rosana, Barreto Mauricio L

机构信息

Instituto de Saúde Coletiva, Federal University of Bahia, Rua Basílio da Gama, s/n, Salvador, Bahia, Brazil

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA.

出版信息

BMJ. 2014 Jul 3;349:g4014. doi: 10.1136/bmj.g4014.

Abstract

OBJECTIVES

To evaluate the impact of Brazil's recently implemented Family Health Program (FHP), the largest primary health care programme in the world, on heart and cerebrovascular disease mortality across Brazil from 2000 to 2009.

DESIGN

Ecological longitudinal design, evaluating the impact of FHP using negative binomial regression models for panel data with fixed effects specifications.

SETTING

Nationwide analysis of data from Brazilian municipalities covering the period from 2000 to 2009.

DATA SOURCES

1622 Brazilian municipalities with vital statistics of adequate quality.

MAIN OUTCOME MEASURES

The annual FHP coverage and the average FHP coverage in previous years were used as main independent variables and classified as none (0%), incipient (<30%), intermediate (30-69%), or consolidated (≥ 70%). Age standardised mortality rates from causes in the group of cerebrovascular (ICD-10 codes I60-69), ischaemic (ICD-10 I20-25), and other forms of heart diseases (ICD-10 I30-52), which were included in the national list of ambulatory care-sensitive conditions, were calculated for each municipality for each year. They accounted for 40% of all deaths from these groups during the study period.

RESULTS

FHP coverage was negatively associated with mortality rates from cerebrovascular and heart diseases (ambulatory care-sensitive conditions) in both unadjusted and adjusted models for demographic, social, and economic confounders. The FHP had no effect on the mortality rate for accidents, used as a control. The rate ratio for the effect of consolidated annual FHP coverage on cerebrovascular disease mortality and on heart disease mortality was 0.82 (95% confidence interval 0.79 to 0.86) and 0.79 (0.75 to 0.80) respectively, reaching the value of 0.69 (0.66 to 0.73) and 0.64 (0.59 to 0.68) when the coverage was consolidated during all the previous eight years. Moreover, FHP coverage increased the number of health education activities, domiciliary visits, and medical consultations and reduced hospitalisation rates for cerebrovascular and heart disease. Several complementary analyses showed quantitatively similar results.

CONCLUSIONS

Comprehensive and community based primary health care programmes, such as the FHP in Brazil, acting through cardiovascular disease prevention, care, and follow-up can contribute to decreased cardiovascular disease morbidity and mortality in a developing country such as Brazil.

摘要

目的

评估巴西近期实施的家庭健康计划(FHP),这是世界上最大的初级卫生保健项目,在2000年至2009年期间对巴西全国心血管疾病死亡率的影响。

设计

生态纵向设计,使用具有固定效应规范的面板数据负二项回归模型评估FHP的影响。

设置

对2000年至2009年期间巴西各市镇的数据进行全国性分析。

数据来源

1622个具有高质量生命统计数据的巴西市镇。

主要观察指标

将年度FHP覆盖率和前几年的平均FHP覆盖率作为主要自变量,并分为无(0%)、初期(<30%)、中期(30-69%)或巩固期(≥70%)。每年为每个市镇计算出国家门诊护理敏感疾病清单中包括的脑血管疾病(国际疾病分类第十版代码I60-69)、缺血性疾病(国际疾病分类第十版I20-25)和其他形式心脏病(国际疾病分类第十版I30-52)的年龄标准化死亡率。在研究期间,这些疾病占这些组所有死亡人数的40%。

结果

在未调整以及针对人口、社会和经济混杂因素进行调整的模型中,FHP覆盖率与脑血管疾病和心脏病(门诊护理敏感疾病)的死亡率呈负相关。FHP对作为对照的事故死亡率没有影响。年度FHP巩固覆盖率对脑血管疾病死亡率和心脏病死亡率的率比分别为0.82(95%置信区间0.79至0.86)和0.79(0.75至0.80),当在之前所有八年中覆盖率均为巩固期时,分别达到0.69(0.66至0.73)和0.64(0.59至0.68)。此外,FHP覆盖率增加了健康教育活动、家访和医疗咨询的次数,并降低了脑血管疾病和心脏病的住院率。多项补充分析显示了定量上相似的结果。

结论

像巴西的FHP这样基于社区的综合初级卫生保健项目,通过心血管疾病的预防、护理和随访发挥作用,有助于在巴西这样的发展中国家降低心血管疾病的发病率和死亡率。

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