Hoeppner J, Marjanovic G, Glatz T, Kulemann B, Hopt U T
Klinik für Allgemein- und Viszeralchirurgie, Universitätsklinikum Freiburg, Hugstetter Str. 55, 79106, Freiburg, Deutschland,
Chirurg. 2014 Jul;85(7):628-35. doi: 10.1007/s00104-014-2783-1.
In the past decades various techniques of esophagectomy for the curative treatment of esophageal cancer have been described. Especially minimally invasive techniques of esophagectomy have been used increasingly in the last decade. Technical issues and results of hybrid laparoscopic-thoracotomic en bloc esophagectomy with intrathoracic esophagogastric anastomosis (HMIE) are presented and discussed in the article.
Between May 2013 and April 2014 a total of 23 patients underwent esophagectomy for esophageal cancer at the University of Freiburg Medical Center. Of these patients 10 were treated by HMIE and the other 13 patients had open esophagectomy (OE).
A detailed description of the operative technique of HMIE is given in a step-by-step fashion. Margin negative resection was achieved in all patients after HMIE and OE and the median lymph node yield of lymphadenectomy in HMIE and OE (29 vs. 27) was nearly the same. The medium duration of the operation (347 min vs. 412 min) and median length of stay on the intensive care unit (6 days vs. 9 days) and hospital (13 days vs. 17 days) were decreased in HMIE patients compared to OE, respectively. Overall postoperative morbidity (40 % vs. 69 %) and especially pulmonary morbidity (10 % vs. 46 %) were also favorable in HMIE. No anastomotic leakage and postoperative in-hospital mortality occurred after HMIE.
The HMIE procedure combines the advantages of minimally invasive operative approaches on especially postoperative pulmonary morbidity after esophagectomy with the high safety of anastomosis and reconstruction achieved in OE. Further advantages are shorter duration of operation and shorter length of hospital stay in HMIE.
在过去几十年中,已经描述了各种用于食管癌根治性治疗的食管切除术技术。特别是在过去十年中,微创食管切除术技术的应用越来越广泛。本文介绍并讨论了胸腔镜辅助腹腔镜整块食管切除术并胸内食管胃吻合术(HMIE)的技术问题和结果。
2013年5月至2014年4月期间,共有23例患者在弗莱堡大学医学中心接受了食管癌食管切除术。其中10例患者接受了HMIE治疗,另外13例患者接受了开放食管切除术(OE)。
本文逐步详细描述了HMIE的手术技术。HMIE和OE术后所有患者均实现了切缘阴性切除,HMIE和OE淋巴结清扫的中位淋巴结收获量(分别为29个和27个)几乎相同。与OE相比,HMIE患者的手术中位时长(分别为347分钟和412分钟)、重症监护病房中位住院时长(分别为6天和9天)以及住院中位时长(分别为13天和17天)均有所缩短。HMIE的总体术后发病率(分别为40%和69%),尤其是肺部发病率(分别为10%和46%)也更有利。HMIE术后未发生吻合口漏和术后院内死亡。
HMIE手术结合了微创术式的优势,尤其是对食管切除术后肺部发病率的优势,以及OE中实现的吻合和重建的高安全性。HMIE的其他优势包括手术时长缩短和住院时间缩短。