Simmons Okeefe L, Kressler Jochen, Nash Mark S
University of Miami Miller School of Medicine, Miami, FL.
University of Miami Miller School of Medicine, Miami, FL.
Arch Phys Med Rehabil. 2014 Dec;95(12):2272-8. doi: 10.1016/j.apmr.2014.06.015. Epub 2014 Jul 5.
Establish reference values of cardiorespiratory fitness applicable to the general, untrained spinal cord injury (SCI) population.
Data were retroactively obtained from 12 studies (May 2004 to May 2012).
An institution-affiliated applied physiology research laboratory.
A total of 153 men and 26 women (age, 18-55y) with chronic SCI (N=179) were included. Participants were not involved in training activities for 1 or more months before testing and were able to complete a progressive resistance exercise test to determine peak oxygen consumption (Vo2peak).
Not applicable.
Percentile ranking (poor<20%; fair; 20%-40%; average, 40%-60%; good, 60%-80%; excellent, 80%-100%) used to establish reference values.
Reference cardiorespiratory fitness values based on functional classification as paraplegic or tetraplegic were established (paraplegic: median, 16.0mL·kg(-1)·min(-1); range, 1.4-35.2mL·kg(-1)·min(-1); tetraplegic: median, 8.8mL·kg(-1)·min(-1); range, 1.5-21.5mL·kg(-1)·min(-1)) for untrained men and women. For the primary outcome measure (Vo2peak), persons with paraplegia had significantly higher values than did persons with tetraplegia (P<.001). Although men had higher values than did women, these differences did not reach significance (P=.256). Regression analysis revealed that motor level of injury was associated with 22.3% of the variability in Vo2peak (P<.001), and an additional 8.7% was associated with body mass index (P<.001). No other measure accounted for additional significant variability.
Established reference fitness values will allow investigators/clinicians to stratify the relative fitness of subjects/patients from the general SCI population. Key determinants are motor level of injury and body habitus, yet most variability in aerobic capacity is not associated with standard measures of SCI status or demographic characteristics.
建立适用于普通未受过训练的脊髓损伤(SCI)人群的心肺适能参考值。
数据追溯自12项研究(2004年5月至2012年5月)。
一所机构附属的应用生理学研究实验室。
共纳入179名患有慢性SCI的男性和女性(年龄18 - 55岁)。参与者在测试前1个月或更长时间未参与训练活动,且能够完成递增负荷运动测试以确定峰值耗氧量(Vo2peak)。
不适用。
用于建立参考值的百分位数排名(差<20%;中等;20% - 40%;平均,40% - 60%;良好,60% - 80%;优秀,80% - 100%)。
建立了基于截瘫或四肢瘫功能分类的心肺适能参考值(截瘫:中位数,16.0mL·kg⁻¹·min⁻¹;范围,1.4 - 35.2mL·kg⁻¹·min⁻¹;四肢瘫:中位数,8.8mL·kg⁻¹·min⁻¹;范围,1.5 - 21.5mL·kg⁻¹·min⁻¹),适用于未受过训练的男性和女性。对于主要观察指标(Vo2peak),截瘫患者的值显著高于四肢瘫患者(P<0.001)。虽然男性的值高于女性,但这些差异未达到显著水平(P = 0.256)。回归分析显示,损伤的运动水平与Vo2peak变异性的22.3%相关(P<0.001),另外8.7%与体重指数相关(P<0.001)。没有其他指标能解释额外的显著变异性。
已建立的参考适能值将使研究者/临床医生能够对普通SCI人群中受试者/患者的相对适能进行分层。关键决定因素是损伤的运动水平和身体状况,但有氧能力的大部分变异性与SCI状态的标准指标或人口统计学特征无关。