干细胞：对完美重编程细胞的探索。 - Suppr

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超能文献

Stem cells: The quest for the perfect reprogrammed cell.

作者信息

Krupalnik Vladislav, Hanna Jacob H

机构信息

Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot 76100, Israel.

出版信息

Nature. 2014 Jul 10;511(7508):160-2. doi: 10.1038/nature13515. Epub 2014 Jul 2.

DOI:10.1038/nature13515

PMID:25008516

Abstract

摘要

相似文献

Stem cells: The quest for the perfect reprogrammed cell.干细胞：对完美重编程细胞的探索。

Nature. 2014 Jul 10;511(7508):160-2. doi: 10.1038/nature13515. Epub 2014 Jul 2.

Conversion of partially reprogrammed cells to fully pluripotent stem cells is associated with further activation of stem cell maintenance- and gamete generation-related genes.部分重编程细胞向完全多能干细胞的转化与干细胞维持和配子生成相关基因的进一步激活有关。

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Innate immunity and epigenetic plasticity in cellular reprogramming.细胞重编程中的固有免疫与表观遗传可塑性

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Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues.多能性与细胞重编程：事实、假说、未解问题。

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Induced pluripotent stem cells free of exogenous reprogramming factors.不含外源性重编程因子的诱导多能干细胞。

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Epigenetic reprogramming and induced pluripotency.表观遗传重编程与诱导多能性。

Development. 2009 Feb;136(4):509-23. doi: 10.1242/dev.020867.

In vivo reprogrammed pluripotent stem cells from teratomas share analogous properties with their in vitro counterparts.来自畸胎瘤的体内重编程多能干细胞与其体外对应物具有相似的特性。

Sci Rep. 2015 Aug 28;5:13559. doi: 10.1038/srep13559.

Linking incomplete reprogramming to the improved pluripotency of murine embryonal carcinoma cell-derived pluripotent stem cells.将不完全重编程与小鼠胚胎癌细胞来源的多能干细胞的增强多能性联系起来。

PLoS One. 2010 Apr 26;5(4):e10320. doi: 10.1371/journal.pone.0010320.

Reprogramming p53-Deficient Germline Stem Cells Into Pluripotent State by Nanog.通过 Nanog 将 p53 缺陷型生殖干细胞重编程为多能性状态。

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Toward pluripotency by reprogramming: mechanisms and application.重编程为多能性：机制与应用。

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Reprogramming for cardiac regeneration.用于心脏再生的重编程。

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Web resources for stem cell research.干细胞研究的网络资源。

Genomics Proteomics Bioinformatics. 2015 Feb;13(1):40-5. doi: 10.1016/j.gpb.2015.01.001. Epub 2015 Feb 18.

本文引用的文献

Abnormalities in human pluripotent cells due to reprogramming mechanisms.人多能细胞因重编程机制而出现的异常。

Nature. 2014 Jul 10;511(7508):177-83. doi: 10.1038/nature13551. Epub 2014 Jul 2.

Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells.人类卵母细胞可将 1 型糖尿病患者的成体体细胞核重编程为二倍体多能干细胞。

Nature. 2014 Jun 26;510(7506):533-6. doi: 10.1038/nature13287. Epub 2014 Apr 28.

Derivation of novel human ground state naive pluripotent stem cells.新型人类原始态未分化多能干细胞的衍生。

Nature. 2013 Dec 12;504(7479):282-6. doi: 10.1038/nature12745. Epub 2013 Oct 30.

Human embryonic stem cells derived by somatic cell nuclear transfer.体细胞核移植技术衍生的人类胚胎干细胞。

Cell. 2013 Jun 6;153(6):1228-38. doi: 10.1016/j.cell.2013.05.006. Epub 2013 May 15.

Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells.重编程因子的比例会影响诱导多能干细胞的表观遗传状态和生物学特性。

Cell Stem Cell. 2011 Dec 2;9(6):588-98. doi: 10.1016/j.stem.2011.11.003.

Somatic coding mutations in human induced pluripotent stem cells.人类诱导多能干细胞中的体细胞编码突变。

Nature. 2011 Mar 3;471(7336):63-7. doi: 10.1038/nature09805.

Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.人类胚胎干细胞和诱导多能干细胞变异参考图谱可实现多能细胞系的高通量特征分析。

Cell. 2011 Feb 4;144(3):439-52. doi: 10.1016/j.cell.2010.12.032.

Epigenetic memory in induced pluripotent stem cells.诱导多能干细胞中的表观遗传记忆。

Nature. 2010 Sep 16;467(7313):285-90. doi: 10.1038/nature09342.

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons.从肌萎缩侧索硬化症患者身上产生的诱导多能干细胞可以分化为运动神经元。

Science. 2008 Aug 29;321(5893):1218-21. doi: 10.1126/science.1158799. Epub 2008 Jul 31.

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.通过特定因子从小鼠胚胎和成体成纤维细胞培养物中诱导多能干细胞。

Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10.

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