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珠江三角洲地区普通人群血液和头发样本中12种重金属的检测与分析

Detection and analysis of 12 heavy metals in blood and hair sample from a general population of Pearl River Delta area.

作者信息

Li Jiqiang, Cen Dongzhi, Huang Donglan, Li Xufeng, Xu Jiajun, Fu Shilin, Cai Rui, Wu Xiaocong, Tang Ming, Sun Yao, Zhang Jiren, Zheng Jingfen

机构信息

Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

出版信息

Cell Biochem Biophys. 2014 Dec;70(3):1663-9. doi: 10.1007/s12013-014-0110-6.

Abstract

To detect the content of 12 heavy metals in blood and hair sample from a general population of Pearl River Delta area, and to analyze the influence of duration of residence, gender, age, smoking and drinking on the heavy metal content. Use inductively coupled plasma mass spectrometry to detect the content of 12 heavy metals lead (Pb), mercury (Hg), cadmium (Cd), aluminum (Al), arsenic (As), copper (Cu), chrome (Cr), manganese (Mn), nickel (Ni), zinc (Zn), tin (Sn) and antimony (Sb) in blood and hair samples of a total of 50 subjects from a general population, collected by multistage stratified cluster random sampling method. The geometric mean of heavy metal content in blood samples of general population (μg/L): blood aluminum 214.00; blood chrome 92.82; blood manganese 21.43; blood nickel 20.59; blood copper 0.67; blood zinc 11.50; blood arsenic 0.55; blood cadmium 2.45; blood tin 0.00; blood antimony 1.92; blood lead 158.84; and blood mercury 1.19. The geometric mean of heavy metal content in hair samples of general population (μg/g): hair aluminum is 84.65; hair chrome 0.00; hair manganese 2.44; hair nickel 0.61; hair copper 28.49; hair zinc 136.65; hair arsenic 0.75; hair cadmium 0.46; hair tin 1.04; hair antimony 0.05; hair lead 8.97; and hair mercury 0.69. Some heavy metals were correlated with duration of residence, gender, age, smoking and drinking. This was the first time that simultaneously detecting heavy metal content in blood and hair was used to analyze the internal heavy metal burden in resident population of Pearl River Delta area. These data can serve as reference for further research.

摘要

检测珠江三角洲地区普通人群血液和头发样本中12种重金属的含量,并分析居住时长、性别、年龄、吸烟和饮酒对重金属含量的影响。采用多阶段分层整群随机抽样方法,收集了50名普通人群的血液和头发样本,使用电感耦合等离子体质谱法检测其中铅(Pb)、汞(Hg)、镉(Cd)、铝(Al)、砷(As)、铜(Cu)、铬(Cr)、锰(Mn)、镍(Ni)、锌(Zn)、锡(Sn)和锑(Sb)这12种重金属的含量。普通人群血液样本中重金属含量的几何均值(μg/L):血铝214.00;血铬92.82;血锰21.43;血镍20.59;血铜0.67;血锌11.50;血砷0.55;血镉2.45;血锡0.00;血锑1.92;血铅158.84;血汞1.19。普通人群头发样本中重金属含量的几何均值(μg/g):发铝84.65;发铬0.00;发锰2.44;发镍0.61;发铜28.49;发锌136.65;发砷0.75;发镉0.46;发锡1.04;发锑0.05;发铅8.97;发汞0.69。部分重金属与居住时长、性别、年龄、吸烟和饮酒相关。这是首次同时检测血液和头发中的重金属含量以分析珠江三角洲地区常住人口体内的重金属负担。这些数据可为进一步研究提供参考。

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