Zhang Sijie, Schönfeld Fabian, Wiskott Laurenz, Manahan-Vaughan Denise
Department of Neurophysiology, Medical Faculty, Ruhr University Bochum Bochum, Germany ; International Graduate School for Neuroscience, Ruhr University Bochum Bochum, Germany.
International Graduate School for Neuroscience, Ruhr University Bochum Bochum, Germany ; Institute for Neural Computation, Ruhr University Bochum Bochum, Germany.
Front Behav Neurosci. 2014 Jun 24;8:222. doi: 10.3389/fnbeh.2014.00222. eCollection 2014.
Effective spatial navigation is enabled by reliable reference cues that derive from sensory information from the external environment, as well as from internal sources such as the vestibular system. The integration of information from these sources enables dead reckoning in the form of path integration. Navigation in the dark is associated with the accumulation of errors in terms of perception of allocentric position and this may relate to error accumulation in path integration. We assessed this by recording from place cells in the dark under circumstances where spatial sensory cues were suppressed. Spatial information content, spatial coherence, place field size, and peak and infield firing rates decreased whereas sparsity increased following exploration in the dark compared to the light. Nonetheless it was observed that place field stability in darkness was sustained by border information in a subset of place cells. To examine the impact of encountering the environment's border on navigation, we analyzed the trajectory and spiking data gathered during navigation in the dark. Our data suggest that although error accumulation in path integration drives place field drift in darkness, under circumstances where border contact is possible, this information is integrated to enable retention of spatial representations.
有效的空间导航依赖于可靠的参考线索，这些线索来自外部环境的感官信息以及内部来源，如前庭系统。来自这些来源的信息整合以路径积分的形式实现航位推算。在黑暗中导航与在感知以体为中心的位置方面的误差积累有关，这可能与路径积分中的误差积累有关。我们通过在空间感官线索被抑制的情况下在黑暗中记录位置细胞来评估这一点。与在光照下相比，在黑暗中探索后，空间信息内容、空间连贯性、位置野大小以及峰值和场内放电率降低，而稀疏性增加。尽管如此，观察到黑暗中位置野的稳定性由一部分位置细胞中的边界信息维持。为了研究遇到环境边界对导航的影响，我们分析了在黑暗中导航期间收集的轨迹和尖峰数据。我们的数据表明，虽然路径积分中的误差积累会导致黑暗中位置野的漂移，但在可能接触边界的情况下，这些信息会被整合以保留空间表征。
