与HIV/AIDS相关的卡波西肉瘤中卡波西肉瘤相关疱疹病毒致癌作用的分子和细胞机制。 - Suppr

Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS.

作者信息

Cavallin Lucas E, Goldschmidt-Clermont Pascal, Mesri Enrique A

机构信息

AIDS Malignancies Scientific Working Group, Miami Center for AIDS Research, Department and Graduate Program of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, United States of America; Viral Oncology Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida, United States of America.

出版信息

PLoS Pathog. 2014 Jul 10;10(7):e1004154. doi: 10.1371/journal.ppat.1004154. eCollection 2014 Jul.

DOI:10.1371/journal.ppat.1004154

PMID:25010730

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4092131/

Abstract

摘要

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Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS.与HIV/AIDS相关的卡波西肉瘤中卡波西肉瘤相关疱疹病毒致癌作用的分子和细胞机制。

PLoS Pathog. 2014 Jul 10;10(7):e1004154. doi: 10.1371/journal.ppat.1004154. eCollection 2014 Jul.

Kaposi's Sarcoma-Associated Herpesvirus: Epidemiology and Molecular Biology.卡波西肉瘤相关疱疹病毒：流行病学与分子生物学

Adv Exp Med Biol. 2017;1018:91-127. doi: 10.1007/978-981-10-5765-6_7.

Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.卡波氏肉瘤相关疱疹病毒的分子生物学与相关致癌作用。

Adv Virus Res. 2010;78:87-142. doi: 10.1016/B978-0-12-385032-4.00003-3.

Pathogenesis of AIDS--related Kaposi's sarcoma. Evidence of a viral etiology.艾滋病相关卡波西肉瘤的发病机制。病毒病因学证据。

Hematol Oncol Clin North Am. 1996 Oct;10(5):1011-21. doi: 10.1016/s0889-8588(05)70381-6.

Induction of hyaluronan production by oncogenic KSHV and the contribution to viral pathogenesis in AIDS patients.致癌性卡波西肉瘤相关疱疹病毒诱导透明质酸生成及其在艾滋病患者病毒发病机制中的作用

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Distinct expression of Kaposi's sarcoma-associated herpesvirus-encoded proteins in Kaposi's sarcoma and multicentric Castleman's disease.卡波西肉瘤相关疱疹病毒编码蛋白在卡波西肉瘤和多中心性Castleman病中的不同表达

Pathol Int. 2006 Oct;56(10):617-24. doi: 10.1111/j.1440-1827.2006.02017.x.

Gene expression profile of AIDS-related Kaposi's sarcoma.艾滋病相关卡波西肉瘤的基因表达谱

BMC Cancer. 2003 Mar 18;3:7. doi: 10.1186/1471-2407-3-7.

Viral gene expression and pathogenesis in three emerging diseases: HIV and AIDS; HTLV-I and HAM/TSP; and HHV-8 and Kaposi's sarcoma.三种新发疾病中的病毒基因表达与发病机制：人类免疫缺陷病毒与艾滋病；人类嗜T淋巴细胞病毒I型与热带痉挛性截瘫；以及人类疱疹病毒8型与卡波西肉瘤。

FEMS Immunol Med Microbiol. 1997 Aug;18(4):301-5. doi: 10.1111/j.1574-695X.1997.tb01059.x.

Demonstration of Kaposi's sarcoma-associated herpes virus cyclin D homolog in cutaneous Kaposi's sarcoma by colorimetric in situ hybridization using a catalyzed signal amplification system.使用催化信号放大系统通过比色原位杂交法在皮肤卡波西肉瘤中证实卡波西肉瘤相关疱疹病毒细胞周期蛋白D同源物

Blood. 1998 May 15;91(10):3825-32.

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma.卡波西肉瘤相关疱疹病毒G蛋白偶联受体作为治疗卡波西肉瘤的治疗靶点。

Cancer Res. 2006 Jan 1;66(1):168-74. doi: 10.1158/0008-5472.CAN-05-1026.

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Disrupting the OTUD4-USP7 deubiquitinase complex to suppress herpesvirus replication: a novel antiviral strategy.破坏OTUD4-USP7去泛素化酶复合物以抑制疱疹病毒复制：一种新型抗病毒策略。

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PLoS Pathog. 2024 Jan 12;20(1):e1011943. doi: 10.1371/journal.ppat.1011943. eCollection 2024 Jan.

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Cureus. 2023 Jul 17;15(7):e42039. doi: 10.7759/cureus.42039. eCollection 2023 Jul.

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NPJ Biofilms Microbiomes. 2023 Jul 12;9(1):48. doi: 10.1038/s41522-023-00413-4.

In Vitro Studies of Pegylated Magnetite Nanoparticles in a Cellular Model of Viral Oncogenesis: Initial Studies to Evaluate Their Potential as a Future Theranostic Tool.聚乙二醇化磁铁矿纳米颗粒在病毒致癌细胞模型中的体外研究：评估其作为未来治疗诊断工具潜力的初步研究

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Human viral oncogenesis: a cancer hallmarks analysis.人类病毒致癌作用：癌症特征分析。

Cell Host Microbe. 2014 Mar 12;15(3):266-82. doi: 10.1016/j.chom.2014.02.011.

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication.生产性感染的鼠类卡波西肉瘤样肿瘤为研究和靶向 KSHV 致癌和复制定义了新的动物模型。

PLoS One. 2014 Jan 28;9(1):e87324. doi: 10.1371/journal.pone.0087324. eCollection 2014.

Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042.艾滋病相关卡波西肉瘤伊马替尼的 II 期临床试验：艾滋病恶性肿瘤联盟方案 042。

J Clin Oncol. 2014 Feb 10;32(5):402-8. doi: 10.1200/JCO.2012.48.6365. Epub 2013 Dec 30.

Gammaherpesviruses and lymphoproliferative disorders.γ疱疹病毒与淋巴组织增生性疾病

Annu Rev Pathol. 2014;9:349-72. doi: 10.1146/annurev-pathol-012513-104656. Epub 2013 Oct 9.

γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis.γ-疱疹病毒编码的 microRNAs 及其在病毒生物学和发病机制中的作用。

Curr Opin Virol. 2013 Jun;3(3):266-75. doi: 10.1016/j.coviro.2013.05.013. Epub 2013 Jun 3.

Cellular origin of Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus-induced cell reprogramming.卡波氏肉瘤的细胞起源和卡波氏肉瘤相关疱疹病毒诱导的细胞重编程。

Trends Cell Biol. 2013 Sep;23(9):421-32. doi: 10.1016/j.tcb.2013.04.001. Epub 2013 May 17.

A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity.在 KSHV 感染的淋巴管内皮细胞中，一种独特的疱疹病毒转录程序导致 mTORC1 的激活和雷帕霉素的敏感性。

Cell Host Microbe. 2013 Apr 17;13(4):429-40. doi: 10.1016/j.chom.2013.03.009.

mTOR inhibitors block Kaposi sarcoma growth by inhibiting essential autocrine growth factors and tumor angiogenesis.mTOR 抑制剂通过抑制必需的自分泌生长因子和肿瘤血管生成来阻断卡波西肉瘤的生长。

Cancer Res. 2013 Apr 1;73(7):2235-46. doi: 10.1158/0008-5472.CAN-12-1851. Epub 2013 Feb 4.

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma.阻断半乳糖凝集素-1 与 N-糖链的相互作用可抑制卡波西肉瘤中缺氧驱动的血管生成和肿瘤发生。

J Exp Med. 2012 Oct 22;209(11):1985-2000. doi: 10.1084/jem.20111665. Epub 2012 Oct 1.

A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.病毒诱导的活性氧在卡波西肉瘤疱疹病毒致瘤中的作用。

Antioxid Redox Signal. 2013 Jan 1;18(1):80-90. doi: 10.1089/ars.2012.4584. Epub 2012 Aug 20.

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Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS.

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