Raj V Stalin, Farag Elmoubasher A B A, Reusken Chantal B E M, Lamers Mart M, Pas Suzan D, Voermans Jolanda, Smits Saskia L, Osterhaus Albert D M E, Al-Mawlawi Naema, Al-Romaihi Hamad E, AlHajri Mohd M, El-Sayed Ahmed M, Mohran Khaled A, Ghobashy Hazem, Alhajri Farhoud, Al-Thani Mohamed, Al-Marri Salih A, El-Maghraby Mamdouh M, Koopmans Marion P G, Haagmans Bart L
Emerg Infect Dis. 2014 Aug;20(8):1339-42. doi: 10.3201/eid2008.140663.
We obtained the full genome of Middle East respiratory syndrome coronavirus (MERS-CoV) from a camel in Qatar. This virus is highly similar to the human England/Qatar 1 virus isolated in 2012. The MERS-CoV from the camel efficiently replicated in human cells, providing further evidence for the zoonotic potential of MERS-CoV from camels.
我们从卡塔尔的一头骆驼身上获得了中东呼吸综合征冠状病毒(MERS-CoV)的全基因组。这种病毒与2012年分离出的人类英格兰/卡塔尔1型病毒高度相似。来自骆驼的MERS-CoV能在人类细胞中有效复制,这为骆驼源MERS-CoV的人畜共患病潜力提供了进一步证据。