Enantioselective adsorption of ibuprofen and lysine in metal-organic frameworks.
作者信息
Bueno-Perez Rocio, Martin-Calvo Ana, Gómez-Álvarez Paula, Gutiérrez-Sevillano Juan J, Merkling Patrick J, Vlugt Thijs J H, van Erp Titus S, Dubbeldam David, Calero Sofia
机构信息
University Pablo de Olavide, Ctra. Utrera km. 1, 41013 Seville, Spain.
出版信息
Chem Commun (Camb). 2014 Sep 25;50(74):10849-52. doi: 10.1039/c4cc03745f.
PMID:25090236
Abstract
This study reveals the efficient enantiomeric separation of bioactive molecules in the liquid phase. Chiral structure HMOF-1 separates racemic mixtures whereas heteroselectivity is observed for scalemic mixtures of ibuprofen using non-chiral MIL-47 and MIL-53. Lysine enantiomers are only separated by HMOF-1. These separations are controlled by the tight confinement of the molecules.
摘要
Zotero 插件