Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Chem Soc Rev. 2014;43(20):6881-93. doi: 10.1039/c4cs00164h.
Bio-inspired nano-materials can be formed by the ordered assembly of elementary building blocks using recognition modules and structural elements. Among the biological sources, peptides and proteins are of special interest due to their role as major structural elements in all living systems, ranging from bacteria to humans in a continuum of magnitudes, from the nano-scale to the macro-scale. Peptides, as short as dipeptides, contain all the molecular information needed to form well-ordered structures at the nano-scale. Here, in light of the significant advancements in the field of peptide nanostructures in the last few years, we provide an updated overview of this subject. The use of these nanostructures was indeed recently demonstrated in various fields including the design of molecular motors based on nanostructure complexation with a metal-organic framework, the delivery of therapeutic agents, the development of energy storage devices and the fabrication of piezoelectric-based sensors.
生物启发的纳米材料可以通过使用识别模块和结构元件对基本构建块进行有序组装来形成。在生物来源中，由于肽和蛋白质在所有生命系统中作为主要结构元件的作用，因此它们特别引人注目，从细菌到人类，跨越了从纳米到宏观的巨大范围。短至二肽的肽包含形成纳米级有序结构所需的所有分子信息。在这里，鉴于近年来肽纳米结构领域的重大进展，我们对该主题进行了更新的概述。这些纳米结构的用途最近确实在各个领域得到了证明，包括基于纳米结构与金属-有机骨架复合的分子马达设计、治疗剂的输送、储能装置的开发和基于压电的传感器的制造。
