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BMJ. 1989 Oct 21;299(6706):1010-2. doi: 10.1136/bmj.299.6706.1010.
2
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4
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6
Evaluation of diagnostic strategies for bladder cancer using computed tomography (CT) urography, flexible cystoscopy and voided urine cytology: results for 778 patients from a hospital haematuria clinic.使用计算机断层扫描(CT)尿路造影、软性膀胱镜检查和尿液细胞学检查评估膀胱癌的诊断策略:来自医院血尿诊所的 778 例患者的结果。
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Who should be included in a clinical trial of screening for bladder cancer?: a decision analysis of data from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.谁应该被纳入膀胱癌筛查临床试验?:来自前列腺癌、肺癌、结直肠癌和卵巢癌筛查试验的数据的决策分析。
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本文引用的文献

1
Study of five hundred patients with asymptomatic microhematuria.对五百例无症状性镜下血尿患者的研究。
J Am Med Assoc. 1956 Jun 16;161(7):610-3. doi: 10.1001/jama.1956.02970070042011.
2
Asymptomatic microscopic hematuria.无症状性镜下血尿。
J Urol. 1980 Sep;124(3):389-91. doi: 10.1016/s0022-5347(17)55461-0.
3
A flexible cystoscope.
Br J Urol. 1984 Dec;56(6):622-4. doi: 10.1111/j.1464-410x.1984.tb06131.x.
4
Dipstick chemical urinalysis: an accurate cost-effective screening test.
J Urol. 1984 Jul;132(1):64-6. doi: 10.1016/s0022-5347(17)49465-1.
5
Early detection of urinary-tractmalignancy by urine testing withreagent strips.
Lancet. 1969 Jun 7;1(7606):1164. doi: 10.1016/s0140-6736(69)91694-8.
6
Screening for hematuria, glucosuria and proteinuria in people aged 55-64. Technical, clinical and cost-benefit experience from a pilot study.
Scand J Prim Health Care. 1985 Feb;3(1):31-4. doi: 10.3109/02813438509017734.
7
The wild goose chase and the elephant's relevance.
JAMA. 1986 Jul 11;256(2):256-7.
8
Asymptomatic microhematuria and urologic disease. A population-based study.无症状性镜下血尿与泌尿系统疾病。一项基于人群的研究。
JAMA. 1986 Jul 11;256(2):224-9.
9
The evaluation of microscopic hematuria: a population-based study.
J Urol. 1987 Nov;138(5):1189-90. doi: 10.1016/s0022-5347(17)43545-2.
10
NHS 1948-88: less ideology, more humanity.英国国家医疗服务体系,1948 - 1988年:更少意识形态,更多人文关怀。
BMJ. 1988 Jul 2;297(6640):1-3. doi: 10.1136/bmj.297.6640.1.

60岁以上男性试纸法血尿与膀胱癌:一项社区研究结果

Dipstick haematuria and bladder cancer in men over 60: results of a community study.

作者信息

Britton J P, Dowell A C, Whelan P

机构信息

St James's University Hospital, Leeds.

出版信息

BMJ. 1989 Oct 21;299(6706):1010-2. doi: 10.1136/bmj.299.6706.1010.

DOI:10.1136/bmj.299.6706.1010
PMID:2511941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1837876/
Abstract

OBJECTIVE

To investigate the prevalence and relevance of dipstick haematuria in a group of men in the community.

DESIGN

Prospective study of elderly men invited to attend a health centre for urine screening as part of a health check.

SETTING

An inner city health centre in Leeds.

SUBJECTS

578 Of 855 men aged 60-85 responding to an invitation to participate.

INTERVENTIONS

The subjects had their urine tested with a dipstick (Multistix) for the presence of blood and then tested their urine once a week for the next 10 weeks. Those with one or more positive test results were offered full urological investigation.

MAIN OUTCOME MEASURE

The prevalence of urological disease in those subjects with dipstick haematuria.

RESULTS

78 Men (13%) had dipstick haematuria on a single test and a further 54 (9%) had evidence of dipstick haematuria when testing their urine once a week during a subsequent 10 week period. Investigation of 87 men disclosed urological disease in 45, including four with a bladder tumour and seven with epithelial dysplasia.

CONCLUSION

Dipstick haematuria is a common incidental finding in men over 60 and is associated with appreciable urological disease. The introduction of less invasive methods of investigation, particularly flexible cystoscopy and ultrasonography, has made investigation of these patients simple and safe and makes screening for bladder cancer in the community more feasible.

摘要

目的

调查社区男性群体中试纸法血尿的患病率及其相关性。

设计

对受邀前往健康中心进行尿液筛查(作为健康检查一部分)的老年男性进行前瞻性研究。

地点

利兹市的一家市中心健康中心。

研究对象

855名年龄在60 - 85岁的男性中,有578人响应邀请参与研究。

干预措施

研究对象用试纸(Multistix)检测尿液中是否有血液,然后在接下来的10周内每周检测一次尿液。试纸检测结果呈阳性一次或多次的人接受全面的泌尿科检查。

主要观察指标

试纸法血尿患者中泌尿系统疾病的患病率。

结果

单次检测时,78名男性(13%)出现试纸法血尿,在随后10周每周检测尿液期间,另有54名男性(9%)有试纸法血尿迹象。对87名男性进行检查后发现,45人患有泌尿系统疾病,其中4人患有膀胱肿瘤,7人有上皮发育异常。

结论

试纸法血尿在60岁以上男性中是常见的偶然发现,且与明显的泌尿系统疾病相关。采用侵入性较小的检查方法,特别是软性膀胱镜检查和超声检查,使这些患者的检查变得简单且安全,并使社区膀胱癌筛查更可行。