Celada A, Maki R
La Jolla Cancer Research Foundation, California 92037.
Mol Cell Biol. 1989 Nov;9(11):5219-22. doi: 10.1128/mcb.9.11.5219-5222.1989.
The X box is a loosely conserved DNA sequence that is located upstream of all major histocompatibility class II genes and is one of the cis-acting regulatory elements. Despite the similarity between all X-box sequences, each promoter-proximal X box in the mouse appears to bind a separate nuclear factor.
X盒是一种保守性较差的DNA序列,位于所有主要组织相容性复合体II类基因的上游,是顺式作用调节元件之一。尽管所有X盒序列之间存在相似性,但小鼠中每个启动子近端X盒似乎都结合一种单独的核因子。