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多种主要组织相容性复合体II类X盒结合蛋白的证据。

Evidence for multiple major histocompatibility class II X-box binding proteins.

作者信息

Celada A, Maki R

机构信息

La Jolla Cancer Research Foundation, California 92037.

出版信息

Mol Cell Biol. 1989 Nov;9(11):5219-22. doi: 10.1128/mcb.9.11.5219-5222.1989.

DOI:10.1128/mcb.9.11.5219-5222.1989
PMID:2513482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC363675/
Abstract

The X box is a loosely conserved DNA sequence that is located upstream of all major histocompatibility class II genes and is one of the cis-acting regulatory elements. Despite the similarity between all X-box sequences, each promoter-proximal X box in the mouse appears to bind a separate nuclear factor.

摘要

X盒是一种保守性较差的DNA序列，位于所有主要组织相容性复合体II类基因的上游，是顺式作用调节元件之一。尽管所有X盒序列之间存在相似性，但小鼠中每个启动子近端X盒似乎都结合一种单独的核因子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44a/363675/684fde8672c4/molcellb00059-0644-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44a/363675/7f6111cca6c1/molcellb00059-0644-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44a/363675/684fde8672c4/molcellb00059-0644-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44a/363675/7f6111cca6c1/molcellb00059-0644-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c44a/363675/684fde8672c4/molcellb00059-0644-b.jpg

相似文献

1
Evidence for multiple major histocompatibility class II X-box binding proteins.多种主要组织相容性复合体II类X盒结合蛋白的证据。
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2
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3
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引用本文的文献

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J Clin Invest. 2001 Feb;107(4):485-93. doi: 10.1172/JCI11696.
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Biochem J. 1996 Feb 1;313 ( Pt 3)(Pt 3):737-44. doi: 10.1042/bj3130737.
3
Repression of major histocompatibility complex IA expression by glucocorticoids: the glucocorticoid receptor inhibits the DNA binding of the X box DNA binding protein.

本文引用的文献

1
Interferon-gamma induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines.γ干扰素可诱导B淋巴细胞、巨噬细胞和髓样细胞系上Ia和H-2抗原的表达增强。
J Immunol. 1983 Aug;131(2):788-93.
2
Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon.免疫干扰素对巨噬细胞系Ia和H-2抗原的诱导作用。
J Immunol. 1983 Jul;131(1):315-8.
3
The murine E alpha immune response gene.小鼠Eα免疫反应基因。
糖皮质激素对主要组织相容性复合体IA表达的抑制作用：糖皮质激素受体抑制X盒DNA结合蛋白的DNA结合。
J Exp Med. 1993 Mar 1;177(3):691-8. doi: 10.1084/jem.177.3.691.
4
X-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.X盒结合蛋白通过与不同的上游W和V元件相互作用，对HLA - DRA基因的转录进行正向和负向调节。
Proc Natl Acad Sci U S A. 1990 Oct;87(19):7703-7. doi: 10.1073/pnas.87.19.7703.
5
Transcription analysis of class II human leukocyte antigen genes from normal and immunodeficient B lymphocytes, using polymerase chain reaction.利用聚合酶链反应对正常和免疫缺陷B淋巴细胞的II类人类白细胞抗原基因进行转录分析。
Mol Cell Biol. 1990 Jul;10(7):3792-6. doi: 10.1128/mcb.10.7.3792-3796.1990.
6
Regulation of the class II-associated invariant chain gene in normal and mutant B lymphocytes.正常和突变B淋巴细胞中II类相关恒定链基因的调控。
Proc Natl Acad Sci U S A. 1990 Jun;87(12):4590-4. doi: 10.1073/pnas.87.12.4590.
7
Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function.主要组织相容性复合体II类DRA启动子功能需要X和Y元件的立体特异性排列。
Mol Cell Biol. 1991 May;11(5):2406-15. doi: 10.1128/mcb.11.5.2406-2415.1991.
8
Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene.亲和纯化的CCAAT盒结合蛋白（YEBP）在功能上调节人类II类主要组织相容性复合体基因和单纯疱疹病毒胸苷激酶基因的表达。
Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1873-7. doi: 10.1073/pnas.88.5.1873.
9
B-cell factor 1 is required for optimal expression of the DRA promoter in B cells.B细胞因子1是B细胞中DRA启动子最佳表达所必需的。
Mol Cell Biol. 1992 May;12(5):2383-90. doi: 10.1128/mcb.12.5.2383-2390.1992.
Cell. 1983 Mar;32(3):745-54. doi: 10.1016/0092-8674(83)90060-0.
4
Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex.小鼠主要组织相容性复合体Eβ链和基因的完整一级结构
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5
Molecular biology of the H-2 histocompatibility complex.H-2组织相容性复合体的分子生物学
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6
Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.HLA-DRα基因组织特异性表达所需的上游DNA序列。
Proc Natl Acad Sci U S A. 1987 Jun;84(12):4254-8. doi: 10.1073/pnas.84.12.4254.
7
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J Immunol. 1986 Sep 1;137(5):1718-23.
8
Three distinct signals can induce class II gene expression in a murine pre-B-cell line.三种不同的信号可在小鼠前B细胞系中诱导II类基因表达。
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9
A CCAAT DNA binding factor consisting of two different components that are both required for DNA binding.一种由两种不同成分组成的CCAAT DNA结合因子，这两种成分对于DNA结合都是必需的。
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B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene.HLA-DRα基因的B细胞特异性及γ干扰素诱导性调控
Proc Natl Acad Sci U S A. 1988 Nov;85(22):8598-602. doi: 10.1073/pnas.85.22.8598.