Phillips D L, Smith A B, Burse V W, Steele G K, Needham L L, Hannon W H
Division of Environmental Health Laboratory Sciences, Centers for Disease Control, Atlanta, Georgia.
Arch Environ Health. 1989 Nov-Dec;44(6):351-4. doi: 10.1080/00039896.1989.9935905.
In 1977 and 1985, serum polychlorinated biphenyl (PCB) concentrations were determined for 58 workers in a Bloomington, Indiana, factory that used polychlorinated biphenyls (PCBs) in capacitor manufacture until 1977. Less chlorinated PCBs were quantitated as Aroclor 1242, and more highly chlorinated PCBs were quantitated as Aroclor 1254. The median half-life was 2.6 y for Aroclor 1242 and 4.8 y for Aroclor 1254. However, the half-life varied inversely with the initial serum concentration. This pattern may be a result of continued low-level exposure, variation in the time of exposure, or enzyme induction by PCBs.
1977年和1985年，对印第安纳州布卢明顿一家工厂的58名工人的血清多氯联苯（PCB）浓度进行了测定。该工厂在1977年之前的电容器制造过程中使用多氯联苯（PCBs）。含氯量较低的多氯联苯被定量为Aroclor 1242，含氯量较高的多氯联苯被定量为Aroclor 1254。Aroclor 1242的中位半衰期为2.6年，Aroclor 1254的中位半衰期为4.8年。然而，半衰期与初始血清浓度呈反比。这种模式可能是由于持续的低水平接触、接触时间的变化或多氯联苯的酶诱导作用所致。
