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坦桑尼亚达累斯萨拉姆市感染艾滋病毒的成年人中超重和肥胖的患病率及风险因素

Prevalence and Risk Factors for Overweight and Obesity among HIV-Infected Adults in Dar es Salaam, Tanzania.

作者信息

Semu Helen, Zack Rachel M, Liu Enju, Hertzmark Ellen, Spiegelman Donna, Sztam Kevin, Hawkins Claudia, Chalamila Guerino, Muya Aisa, Siril Hellen, Mwiru Ramadhani, Mtasiwa Deo, Fawzi Wafaie

机构信息

Department of Preventive Services, Ministry of Health and Social Welfare, Dar es Salaam, Tanzania

Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.

出版信息

J Int Assoc Provid AIDS Care. 2016 Nov;15(6):512-521. doi: 10.1177/2325957414542574. Epub 2014 Aug 21.

Abstract

BACKGROUND

Overweight and obesity are increasingly prevalent among HIV-infected populations. We describe their prevalence and associated risk factors among HIV-infected adults in Dar es Salaam, Tanzania.

METHODS

A cross-sectional study was conducted to determine the proportion of patients who were overweight or obese at enrollment to care and treatment centres from 2004 to 2011. Multivariate relative risk regression models were fit to identify risk factors.

RESULTS

A total of 53 825 patients were included in the analysis. In all, 16% of women and 8% of men were overweight, while 7% and 2% were obese, respectively. In multivariate analyses, older age, higher CD4 count, higher hemoglobin levels, female sex, and being married were associated with obesity and overweight. World Health Organization HIV disease stage, tuberculosis history, and previous antiretroviral therapy were inversely associated with obesity and overweight.

CONCLUSION

Overweight and obesity were highly prevalent among HIV-infected patients. Screening for overweight and obesity and focused interventions should be integrated into HIV care.

摘要

背景

超重和肥胖在艾滋病毒感染人群中越来越普遍。我们描述了坦桑尼亚达累斯萨拉姆艾滋病毒感染成年人中超重和肥胖的患病率及其相关危险因素。

方法

开展了一项横断面研究,以确定2004年至2011年在护理和治疗中心登记时超重或肥胖患者的比例。采用多变量相对风险回归模型来识别危险因素。

结果

共有53825名患者纳入分析。总体而言,16%的女性和8%的男性超重,而肥胖者分别为7%和2%。在多变量分析中,年龄较大、CD4细胞计数较高、血红蛋白水平较高、女性性别以及已婚与肥胖和超重相关。世界卫生组织艾滋病毒疾病分期、结核病史和既往抗逆转录病毒治疗与肥胖和超重呈负相关。

结论

超重和肥胖在艾滋病毒感染患者中非常普遍。超重和肥胖筛查以及针对性干预应纳入艾滋病毒护理。

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