Herlev Hospital, University of Copenhagen, Department of Surgery, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Herlev Hospital, University of Copenhagen, Department of Surgery, Herlev Ringvej 75, DK-2730 Herlev, Denmark.
Sleep Med Rev. 2015 Apr;20:73-83. doi: 10.1016/j.smrv.2014.07.002. Epub 2014 Jul 14.
Sleep disturbances are a prevalent and disabling problem for patients with cancer. Sleep disturbances are present throughout the cancer trajectory, especially during oncological treatment. Previously sleep disturbances have primarily been quantified with subjective rating scales. Actigraphy is an easy to use, non-invasive method for objective measurement of sleep. We systematically reviewed the literature for studies using actigraphy to measure sleeping habits of patients with cancer, undergoing oncological treatment. Our study furthermore reviewed studies with interventions designed to reduce sleep disturbances in the patient population. 19 studies were included in the final review of which 13 had a descriptive study design and six included some kind of intervention. The studies were primarily performed in patients with breast cancer undergoing chemotherapy. We found that sleep disturbances are prevalent, and persistent in patients with cancer. The sleep disturbances seem to be aggravated by chemotherapy treatment and accumulate as the treatment continues. Sleep disturbances need further attention among clinicians working with patients with cancer.
睡眠障碍是癌症患者普遍存在且致残的问题。睡眠障碍贯穿癌症病程始终，尤其是在肿瘤治疗期间。既往睡眠障碍主要通过主观评分量表进行量化。活动记录仪是一种简单易用、非侵入性的客观测量睡眠的方法。我们系统性地回顾了使用活动记录仪测量接受肿瘤治疗的癌症患者睡眠习惯的研究文献。我们的研究还回顾了旨在减少患者人群中睡眠障碍的干预措施研究。最终综述纳入了 19 项研究，其中 13 项为描述性研究设计，6 项包括某种干预措施。这些研究主要在接受化疗的乳腺癌患者中进行。我们发现，癌症患者普遍存在且持续存在睡眠障碍。化疗治疗似乎加重了睡眠障碍，并随着治疗的继续而积累。在与癌症患者合作的临床医生中，需要进一步关注睡眠障碍。
