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息肉样脉络膜血管病变的频域光学相干断层扫描结果提示为1型新生血管生长模式。

Spectral-domain optical coherence tomography findings in polypoidal choroidal vasculopathy suggest a type 1 neovascular growth pattern.

作者信息

Alshahrani Saeed T, Al Shamsi Hanan N, Kahtani Eman S, Ghazi Nicola G

机构信息

King Fahad Specialist Hospital, Dammam, Saudi Arabia ; King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

出版信息

Clin Ophthalmol. 2014 Sep 1;8:1689-95. doi: 10.2147/OPTH.S68471. eCollection 2014.

Abstract

PURPOSE

To report spectral-domain optical coherence tomography (SD-OCT) findings in polypoidal choroidal vasculopathy (PCV).

PATIENTS AND METHODS

Seventeen eyes of 15 consecutive patients diagnosed with PCV based on typical clinical and angiographic findings were imaged with macular SD-OCT including line scans passing through the polyps.

RESULTS

SD-OCT findings included typical and atypical retinal pigment epithelial (RPE) detachments and subretinal and intraretinal fluid in all eyes. In the areas corresponding to the polypoidal lesions, well-delineated round-oval, sub-RPE cavities were present and were adherent to the posterior surface of the detached RPE above Bruch membrane. No retinal or choroidal connections to the cavities were noted.

CONCLUSION

These SD-OCT findings document that the vascular lesions in PCV are not located in the inner choroid, but in the sub-RPE space, suggesting that PCV is a variant of type 1 choroidal neovascularization rather than a distinct clinical entity as initially thought.

摘要

目的

报告息肉样脉络膜血管病变(PCV)的光谱域光学相干断层扫描(SD-OCT)检查结果。

患者与方法

对15例连续诊断为PCV的患者的17只眼进行了黄斑SD-OCT成像,包括穿过息肉的线扫描,诊断基于典型的临床和血管造影表现。

结果

SD-OCT检查结果包括所有眼中典型和非典型的视网膜色素上皮(RPE)脱离以及视网膜下和视网膜内液体积聚。在与息肉样病变对应的区域,存在边界清晰的圆形至椭圆形、RPE下腔,且附着于Bruch膜上方脱离的RPE后表面。未发现视网膜或脉络膜与这些腔有连接。

结论

这些SD-OCT检查结果表明,PCV中的血管病变并非位于脉络膜内层,而是位于RPE下间隙,提示PCV是1型脉络膜新生血管的一种变体,而非最初认为的一种独特临床实体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbdd/4159396/1d48f39d9acb/opth-8-1689Fig1.jpg

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