Alshahrani Saeed T, Al Shamsi Hanan N, Kahtani Eman S, Ghazi Nicola G
King Fahad Specialist Hospital, Dammam, Saudi Arabia ; King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Clin Ophthalmol. 2014 Sep 1;8:1689-95. doi: 10.2147/OPTH.S68471. eCollection 2014.
To report spectral-domain optical coherence tomography (SD-OCT) findings in polypoidal choroidal vasculopathy (PCV).
Seventeen eyes of 15 consecutive patients diagnosed with PCV based on typical clinical and angiographic findings were imaged with macular SD-OCT including line scans passing through the polyps.
SD-OCT findings included typical and atypical retinal pigment epithelial (RPE) detachments and subretinal and intraretinal fluid in all eyes. In the areas corresponding to the polypoidal lesions, well-delineated round-oval, sub-RPE cavities were present and were adherent to the posterior surface of the detached RPE above Bruch membrane. No retinal or choroidal connections to the cavities were noted.
These SD-OCT findings document that the vascular lesions in PCV are not located in the inner choroid, but in the sub-RPE space, suggesting that PCV is a variant of type 1 choroidal neovascularization rather than a distinct clinical entity as initially thought.
报告息肉样脉络膜血管病变(PCV)的光谱域光学相干断层扫描(SD-OCT)检查结果。
对15例连续诊断为PCV的患者的17只眼进行了黄斑SD-OCT成像,包括穿过息肉的线扫描,诊断基于典型的临床和血管造影表现。
SD-OCT检查结果包括所有眼中典型和非典型的视网膜色素上皮(RPE)脱离以及视网膜下和视网膜内液体积聚。在与息肉样病变对应的区域,存在边界清晰的圆形至椭圆形、RPE下腔,且附着于Bruch膜上方脱离的RPE后表面。未发现视网膜或脉络膜与这些腔有连接。
这些SD-OCT检查结果表明,PCV中的血管病变并非位于脉络膜内层,而是位于RPE下间隙,提示PCV是1型脉络膜新生血管的一种变体,而非最初认为的一种独特临床实体。