Magdaleno Anahí, Juárez Angela Beatriz, Dragani Valeria, Saenz Magalí Elizabeth, Paz Marta, Moretton Juan
Cátedra de Higiene y Sanidad, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, 4° Piso, C1113AAC Buenos Aires, Argentina.
Departamento de Biodiversidad y Biología Experimental y Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EGA Buenos Aires, Argentina ; Instituto de Biodiversidad y Biología Experimental y Aplicada (IBBEA-CONICET), C1428EGA Buenos Aires, Argentina.
J Toxicol. 2014;2014:248461. doi: 10.1155/2014/248461. Epub 2014 Aug 21.
Hospital wastewater (HWW) constitutes a potential risk to the ecosystems and human health due to the presence of toxic and genotoxic chemical compounds. In the present work we investigated toxicity and genotoxicity of wastewaters from the public hospital of Buenos Aires (Argentina). The effluent from the sewage treatment plant (STP) serving around 10 million inhabitants was also evaluated. The study was carried out between April and September 2012. Toxicity and genotoxicity assessment was performed using the green algae Pseudokirchneriella subcapitata and the Allium cepa test, respectively. Toxicity assay showed that 55% of the samples were toxic to the algae (%I of growth between 23.9 and 54.8). The A. cepa test showed that 40% of the samples were genotoxic. The analysis of chromosome aberrations (CA) and micronucleus (MN) showed no significant differences between days and significant differences between months. The sample from the STP was not genotoxic to A. cepa but toxic to the algae (%I = 41%), showing that sewage treatment was not totally effective. This study highlights the need for environmental control programs and the establishment of advanced and effective effluent treatment plants in the hospitals, which are merely dumping the wastewaters in the municipal sewerage system.
由于存在有毒和具有基因毒性的化合物,医院废水(HWW)对生态系统和人类健康构成潜在风险。在本研究中,我们调查了布宜诺斯艾利斯(阿根廷)公立医院废水的毒性和基因毒性。还对服务约1000万居民的污水处理厂(STP)的出水进行了评估。该研究于2012年4月至9月进行。分别使用绿藻羊角月牙藻和洋葱根尖试验进行毒性和基因毒性评估。毒性试验表明,55%的样品对藻类有毒(生长抑制率在23.9%至54.8%之间)。洋葱根尖试验表明,40%的样品具有基因毒性。染色体畸变(CA)和微核(MN)分析显示,不同日期之间无显著差异,但不同月份之间存在显著差异。污水处理厂的样品对洋葱根尖无基因毒性,但对藻类有毒(生长抑制率=41%),表明污水处理并非完全有效。这项研究强调了环境控制计划的必要性,以及在医院建立先进有效的污水处理厂的必要性,目前医院只是将废水排入城市污水系统。