Schleider Jessica L, Ginsburg Golda S, Keeton Courtney P, Weisz John R, Birmaher Boris, Kendall Phillip C, Piacentini John, Sherrill Joel, Walkup John T
Department of Psychology.
Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine.
J Consult Clin Psychol. 2015 Feb;83(1):213-24. doi: 10.1037/a0037935. Epub 2014 Sep 15.
Research has examined the effects of parental psychopathology, family functioning, and caregiver strain on treatment response in anxious youths. Although these variables have shown individual links to youth treatment response, theoretical models for their combined effects remain unexplored. This study tested the hypothesis that improvements in family functioning and reductions in caregiver strain explained the effects of parental psychopathology on youth treatment outcome in an anxiety treatment trial.
A multiple mediation technique was used to test the proposed model across independent evaluator (IE), parent, and youth informants in 488 youths, aged 7-17 years (50% female; mean age = 10.7) meeting Diagnostic and Statistical Manual of Mental Disorders criteria for social phobia, separation anxiety, and/or generalized anxiety disorder. Youths were randomized to receive 12 weeks of cognitive-behavioral treatment (Coping Cat), medication (sertraline), their combination, or a pill placebo. At pre- and posttreatment, parents completed self-report measures of global psychopathology symptoms, family functioning, and caregiver strain; parents, youths, and IEs rated youths' anxiety symptom severity.
Changes in family functioning and caregiver strain jointly explained relations between parental psychopathology and reductions in youth anxiety. Specifically, across IE and parent informants, families with higher pretreatment parental psychopathology showed more improvement in family functioning and caregiver strain, which in turn predicted greater youth anxiety reductions. Further, higher pretreatment parental psychopathology predicted greater caregiver strain reductions and, in turn, greater youth anxiety reductions, based on youths' reports of their own anxiety.
Findings suggest that improvements in family functioning and reductions in caregiver strain can influence treatment outcomes for anxious youths, especially among youths with more distressed parents.
研究探讨了父母精神病理学、家庭功能及照料者压力对焦虑青少年治疗反应的影响。尽管这些变量已显示出与青少年治疗反应存在个体关联,但其综合作用的理论模型仍未得到探索。本研究检验了以下假设:在一项焦虑症治疗试验中,家庭功能的改善和照料者压力的减轻可解释父母精神病理学对青少年治疗结果的影响。
采用多重中介技术,对488名年龄在7至17岁(50%为女性;平均年龄 = 10.7岁)、符合《精神障碍诊断与统计手册》社交恐惧症、分离焦虑症和/或广泛性焦虑症标准的青少年,通过独立评估者(IE)、父母及青少年自身提供的信息来检验所提出的模型。青少年被随机分配接受为期12周的认知行为治疗(应对猫疗法)、药物治疗(舍曲林)、二者联合治疗或安慰剂治疗。在治疗前和治疗后,父母完成关于总体精神病理学症状、家庭功能及照料者压力的自我报告测量;父母、青少年及独立评估者对青少年的焦虑症状严重程度进行评分。
家庭功能的变化和照料者压力共同解释了父母精神病理学与青少年焦虑减轻之间的关系。具体而言,在独立评估者和父母提供的信息中,治疗前父母精神病理学程度较高的家庭在家庭功能和照料者压力方面改善更大,这反过来又预示着青少年焦虑减轻程度更大。此外,根据青少年对自身焦虑的报告,治疗前父母精神病理学程度较高预示着照料者压力减轻程度更大,进而青少年焦虑减轻程度也更大。
研究结果表明,家庭功能的改善和照料者压力的减轻可影响焦虑青少年的治疗结果,尤其是在父母困扰程度较高的青少年中。