Mangal Chris N, Maryogo-Robinson Lucy
Biosecur Bioterror. 2014 Sep-Oct;12(5):274-83. doi: 10.1089/bsp.2014.0039.
Promoting global health security as an international priority is a challenge; the US Centers for Disease Control and Prevention (CDC) in its Global Health Security Agenda has articulated the importance of accelerating progress toward a world safe and secure from infectious disease threats. The goals are to (1) prevent and reduce the likelihood of outbreaks-natural, accidental, or intentional; (2) detect threats early to save lives; and (3) respond rapidly and effectively using multisectoral, international coordination and communication. Foundational to this agenda is the World Health Organization (WHO) Revised International Health Regulations (IHR) of 2005, which provide the legal framework for countries to strengthen their health systems in order to be able to respond to any public health emergency of international concern. This article proposes leveraging the distributed structure of the US-managed Laboratory Response Network for Biological Threats Preparedness (LRN-B) to develop the core capacity of laboratory testing and to fulfill the laboratory-strengthening component of the Global Health Security Agenda. The LRN model offers an effective mechanism to detect and respond to public health emergencies of international concern.
将促进全球卫生安全作为一项国际优先事项是一项挑战；美国疾病控制与预防中心（CDC）在其全球卫生安全议程中明确了加快迈向一个免受传染病威胁的安全世界的重要性。目标是：（1）预防和降低疫情爆发的可能性——自然的、意外的或故意的；（2）尽早发现威胁以挽救生命；（3）通过多部门、国际协调与沟通迅速有效地做出应对。该议程的基础是世界卫生组织（WHO）2005年修订的《国际卫生条例》（IHR），它为各国加强卫生系统提供了法律框架，以便能够应对任何国际关注的突发公共卫生事件。本文提议利用美国管理的生物威胁防范实验室反应网络（LRN - B）的分布式结构来发展实验室检测的核心能力，并履行全球卫生安全议程中实验室强化部分的职责。LRN模式提供了一种有效的机制来检测和应对国际关注的突发公共卫生事件。
