Yao Fujun, Zhang Yani, Wei Yongfeng, Kang Xiaofeng
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an 710069, P. R. China.
Chem Commun (Camb). 2014 Nov 18;50(89):13853-6. doi: 10.1039/c4cc06135g.
Nanopore analysis has emerged as the simplest single-molecule technique. We combined DNA probes with a nanopore electrochemical sensor for the rapid and sensitive detection of pathogenic DNA. The novel nanopore biosensor allows the single-base discrimination and detection of picomolar DNA in serum samples.
纳米孔分析已成为最简单的单分子技术。我们将DNA探针与纳米孔电化学传感器相结合，用于快速、灵敏地检测致病DNA。这种新型纳米孔生物传感器能够对血清样本中的皮摩尔级DNA进行单碱基识别和检测。
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