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Braz J Microbiol. 2010 Apr;41(2):381-5. doi: 10.1590/S1517-838220100002000019. Epub 2010 Jun 1.
3
Molecular detection of Anaplasma platys and Babesia gibsoni in dogs in Malaysia.马来西亚犬类中嗜吞噬细胞无形体和吉氏巴贝斯虫的分子检测
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Co-infection with Anaplasma platys, Bartonella henselae and Candidatus Mycoplasma haematoparvum in a veterinarian.兽医同时感染阿纳普勒马 platys、巴尔通体 henselae 和血液巴尔通体。
Parasit Vectors. 2013 Apr 15;6:103. doi: 10.1186/1756-3305-6-103.
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First description of natural Ehrlichia canis and Anaplasma platys infections in dogs from Argentina.首次描述来自阿根廷的犬自然感染埃立克体属和无形体属。
Comp Immunol Microbiol Infect Dis. 2013 Mar;36(2):169-73. doi: 10.1016/j.cimid.2012.11.008. Epub 2012 Dec 27.
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First case of Anaplasma platys infection in a dog from Croatia.首例来自克罗地亚的平体无浆体感染犬病例。
Parasit Vectors. 2012 Mar 9;5:49. doi: 10.1186/1756-3305-5-49.
7
Emergence of a new pathogenic Ehrlichia species, Wisconsin and Minnesota, 2009.2009 年，新型致病性埃立克体在威斯康星州和明尼苏达州出现。
N Engl J Med. 2011 Aug 4;365(5):422-9. doi: 10.1056/NEJMoa1010493.
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Evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens.幼龄犬自然感染媒介传播病原体的临床、血液学和生化学检查结果的演变。
Vet Microbiol. 2011 Apr 21;149(1-2):206-12. doi: 10.1016/j.vetmic.2010.10.006. Epub 2010 Oct 16.
9
Experimental infection and co-infection of dogs with Anaplasma platys and Ehrlichia canis: hematologic, serologic and molecular findings.犬感染血小板无形体和犬埃立克体的实验性感染及共感染：血液学、血清学和分子学研究结果
Parasit Vectors. 2010 Apr 8;3(1):33. doi: 10.1186/1756-3305-3-33.
10
Current management of human granulocytic anaplasmosis, human monocytic ehrlichiosis and Ehrlichia ewingii ehrlichiosis.人粒细胞无形体病、人单核细胞埃立克体病和尤因埃立克体病的当前管理
Expert Rev Anti Infect Ther. 2009 Aug;7(6):709-22. doi: 10.1586/eri.09.44.

病例报告：委内瑞拉两名女性感染血小板无形体的分子证据。

Case report: Molecular evidence of Anaplasma platys infection in two women from Venezuela.

作者信息

Arraga-Alvarado Cruz M, Qurollo Barbara A, Parra Omaira C, Berrueta Maribel A, Hegarty Barbara C, Breitschwerdt Edward B

机构信息

Unidad de Investigaciones Clínicas, Facultad de Ciencias Veterinarias, Universidad del Zulia, Maracaibo, Venezuela; Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Unidad de Investigaciones Clínicas, Facultad de Ciencias Veterinarias, Universidad del Zulia, Maracaibo, Venezuela; Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina

出版信息

Am J Trop Med Hyg. 2014 Dec;91(6):1161-5. doi: 10.4269/ajtmh.14-0372. Epub 2014 Sep 29.

DOI:10.4269/ajtmh.14-0372
PMID:25266347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4257640/
Abstract

This article presents two case reports of Anaplasma platys detection in two women from Venezuela. Both patients were exposed to Rhipicephalus sanguineus, the presumed tick vector, and experienced chronic, nonspecific clinical signs including headaches and muscle pains. Intra-platelet inclusion bodies resembling A. platys were observed in buffy coat smears and A. platys DNA was amplified and sequenced from whole blood; however, treatment with doxycycline did not alleviate their symptoms. These cases provide further support for A. platys as a zoonotic tick-borne pathogen, most likely of low pathogenicity; nonetheless, the cause of illness in humans by A. platys is yet to be confirmed.

摘要

本文介绍了在两名来自委内瑞拉的女性中检测到嗜吞噬细胞无形体的两例病例报告。两名患者均接触过推测为传播媒介的血红扇头蜱，并出现了包括头痛和肌肉疼痛在内的慢性非特异性临床症状。在血沉棕黄层涂片上观察到类似于嗜吞噬细胞无形体的血小板内包涵体，并且从全血中扩增并测序了嗜吞噬细胞无形体的DNA；然而，用强力霉素治疗并未缓解她们的症状。这些病例进一步支持嗜吞噬细胞无形体作为一种人畜共患的蜱传病原体，其致病性很可能较低；尽管如此，嗜吞噬细胞无形体导致人类疾病的原因尚未得到证实。