St, Mary's Hospital, Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, #62 Yeouido-dong, Yeongdeungpo-gu, Seoul 150-713, Korea.
BMC Ophthalmol. 2014 Oct 3;14:117. doi: 10.1186/1471-2415-14-117.
To report our experience with small incision lenticule extraction ("SMILE") for myopia treatment.
In this prospective clinical study, we evaluated 447 eyes from 224 patients with myopia, with and without astigmatism. We followed the patients for 6 months after SMILE.
The mean (±standard deviation, SD) spherical equivalent was -6.75 ± 1.65 diopters (D) preoperatively and -0.21 ± 0.37 D at 6 months postoperatively. Our data showed that 97.9% of eyes were within ±1.0 D and 86.1% were within ±0.5 D of the intended correction. Furthermore, 79.8% had an uncorrected distance visual acuity (UDVA) of 0 logMAR or less (20/20 or better in the Snellen equivalent) 6 months after surgery. Additionally, 48.5% remained unchanged, 41% gained one line of corrected distance visual acuity (CDVA), 7.2% gained two lines of CDVA, 3.3% lost one line of CDVA, and 0.3% lost two or more lines of CDVA. Age was the only predictor for worsening UDVA at 6 months postoperatively in linear regression analyses (0.07 decrease logMAR per increased 10 years of age; P < 0.05). No predictor showed an association with error in spherical equivalent refraction at 6 months postoperatively.
SMILE is an effective and safe refractive surgery. Age was the only predictor that influenced visual outcome, but its effect appeared clinically insignificant. Faster visual recovery is also expected with improved surgical technique.
报告我们在近视治疗中小切口透镜切除术（“SMILE”）的经验。
在这项前瞻性临床研究中，我们评估了 224 名近视伴或不伴散光患者的 447 只眼。我们在 SMILE 术后 6 个月对患者进行随访。
平均（±标准差，SD）术前球镜等效值为-6.75±1.65 屈光度（D），术后 6 个月为-0.21±0.37 D。我们的数据显示，97.9%的眼在±1.0 D 以内，86.1%的眼在±0.5 D 以内。此外，79.8%的眼术后 6 个月未矫正距离视力（UDVA）为 0 对数视力或更低（20/20 或更好的 Snellen 等价物）。此外，48.5%保持不变，41%提高一行矫正距离视力（CDVA），7.2%提高两行 CDVA，3.3%降低一行 CDVA，0.3%降低两行或更多行 CDVA。线性回归分析显示，年龄是术后 6 个月 UDVA 恶化的唯一预测因素（每增加 10 岁，logMAR 降低 0.07；P<0.05）。在术后 6 个月，没有预测因子与球镜等效折射误差相关。
SMILE 是一种有效且安全的屈光手术。年龄是影响视力结果的唯一预测因素，但影响程度在临床上无足轻重。随着手术技术的改进，也有望更快地恢复视力。
