Mishra Srikanta K, Abdala Carolina
J Speech Lang Hear Res. 2015 Feb;58(1):122-34. doi: 10.1044/2014_JSLHR-H-14-0013.
The purpose of this study was to assess the repeatability of a fine-resolution, distortion product otoacoustic emission (DPOAE)-based assay of the medial olivocochlear (MOC) reflex in normal-hearing adults.
Data were collected during 36 test sessions from 4 normal-hearing adults to assess short-term stability and 5 normal-hearing adults to assess long-term stability. DPOAE level and phase measurements were recorded with and without contralateral acoustic stimulation. MOC reflex indices were computed by (a) noting contralateral acoustic stimulation-induced changes in DPOAE level (both absolute and normalized) at fine-structure peaks, (b) recording the effect as a vector difference, and (c) separating DPOAE components and considering a component-specific metric.
Analyses indicated good repeatability of all indices of the MOC reflex in most frequency ranges. Short- and long-term repeatability were generally comparable. Indices normalized to a subject's own baseline fared best, showing strong short- and long-term stability across all frequency intervals.
These results suggest that fine-resolution DPOAE-based measures of the MOC reflex measured at strategic frequencies are stable, and natural variance from day-to-day or week-to-week durations is small enough to detect between-group differences and possibly to monitor intervention-related success. However, this is an empirical question that must be directly tested to confirm its utility.
本研究旨在评估基于高分辨率畸变产物耳声发射（DPOAE）的正常听力成年人内侧橄榄耳蜗（MOC）反射检测方法的可重复性。
从4名正常听力成年人收集了36次测试数据以评估短期稳定性，从5名正常听力成年人收集数据以评估长期稳定性。在有和没有对侧声刺激的情况下记录DPOAE水平和相位测量值。MOC反射指数通过以下方式计算：（a）记录在精细结构峰值处对侧声刺激引起的DPOAE水平变化（绝对变化和归一化变化）；（b）将该效应记录为矢量差；（c）分离DPOAE成分并考虑特定成分指标。
分析表明，在大多数频率范围内，MOC反射的所有指标都具有良好的可重复性。短期和长期可重复性通常相当。以受试者自身基线进行归一化的指标表现最佳，在所有频率区间均显示出强大的短期和长期稳定性。
这些结果表明，在特定频率下基于高分辨率DPOAE测量的MOC反射是稳定的，日常或每周的自然变异性足够小，足以检测组间差异，并可能用于监测与干预相关的成功情况。然而，这是一个必须直接进行测试以确认其效用的实证问题。
