Zhu X, Ye H, Yang J, Lu Y
Department of Ophthalmology, Eye and Ear, Nose, and Throat Hospital of Fudan University, Shanghai, People's Republic of China.
Eye (Lond). 2015 Jan;29(1):98-105. doi: 10.1038/eye.2014.242. Epub 2014 Oct 17.
To evaluate the effect of pupil size on higher-order aberrations (HOAs) in high-myopic pseudophakic eyes with posterior staphyloma using KR-1W aberrometer.
Forty eyes of 40 high-myopic cataract patients with posterior staphyloma and 20 eyes of 20 age-related cataract patients with normal axial length were recruited. At 1 month after phacoemulsification and intraocular lens implantation, ocular and internal HOAs as well as the visual quality data in the two groups were evaluated with KR-1W analyzer before and after mydriasis.
Compared with normal axial length eyes, high-myopic pseudophakic eyes with posterior staphyloma had significantly lower values of internal coma both under 4-mm and 6-mm pupil sizes (P<0.001 and 0.020), as well as internal total HOAs (P<0.001) and third-order aberrations at 6-mm pupil size (P=0.018). Statistically significant differences were also found in the variation from 4- to 6-mm pupil sizes for internal coma (P=0.001), internal third-order aberrations (P=0.009), internal total HOAs (P=0.007), and ocular coma aberrations (P=0.006) between two groups. After mydriasis, Strehl ratio increased significantly in high-myopic eyes, whereas decreased slightly in normal axial length eyes (P=0.032 when compared with the variation between the two groups). Statistically significant differences were also found for the variation of modulation transfer functions (MTFs) at frequencies of 15, 30, 45, and 60 cycles/degree between the two groups (P=0.002, 0.002, 0.004, and 0.010, respectively).
High-myopic pseudophakic eyes with posterior staphyloma had significantly lower internal coma and less coma variations during mydriasis.
使用KR-1W像差仪评估瞳孔大小对伴有后巩膜葡萄肿的高度近视人工晶状体眼高阶像差（HOAs）的影响。
招募40例伴有后巩膜葡萄肿的高度近视白内障患者的40只眼和20例眼轴长度正常的年龄相关性白内障患者的20只眼。在超声乳化白内障吸除术和人工晶状体植入术后1个月，使用KR-1W分析仪在散瞳前后评估两组的眼内和内部HOAs以及视觉质量数据。
与眼轴长度正常的眼睛相比，伴有后巩膜葡萄肿的高度近视人工晶状体眼在4mm和6mm瞳孔大小下的内部彗差值均显著较低（P<0.001和0.020），以及内部总HOAs（P<0.001）和在6mm瞳孔大小下的三阶像差（P=0.018）。两组之间在4至6mm瞳孔大小变化时，内部彗差（P=0.001）、内部三阶像差（P=0.009）、内部总HOAs（P=0.007）和眼彗差（P=0.006）也存在统计学显著差异。散瞳后，高度近视眼的斯特列尔比值显著增加，而眼轴长度正常的眼睛略有下降（与两组之间的变化相比，P=0.032）。两组之间在15、30、45和60周/度频率下的调制传递函数（MTF）变化也存在统计学显著差异（分别为P=0.002、0.002、0.004和0.010）。
伴有后巩膜葡萄肿的高度近视人工晶状体眼内部彗差显著较低，散瞳期间彗差变化较小。
