甲状腺混合性髓样-乳头状癌：一种罕见的甲状腺癌变体。

Jain Manjula, Verma Deepti, Thomas Shaji, Chauhan Richa

Department of Pathology, Senior Resident, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.

Department of Surgery, Lady Hardinge Medical College, New Delhi, India.

J Lab Physicians. 2014 Jul;6(2):133-5. doi: 10.4103/0974-2727.141520.

Mixed medullary-papillary carcinoma of the thyroid, a variant of medullary carcinoma is a rare thyroid malignancy accounting for less than 1% of the thyroid malignancies. We are presenting a case of 57-year-old lady with complaints of gradually increasing thyroid swelling for 1½ months. Fine-needle aspiration was suggestive of medullary carcinoma. Serum calcitonin levels were elevated. The patient underwent total thyoidectomy with regional cervical lymph node excision. Histopathologically, the diagnosis of mixed medullary-papillary carcinoma of the thyroid was made. It is important to know about this entity due to its prognostic implications and to prevent any diagnostic dilemmas.

甲状腺混合性髓样-乳头状癌是髓样癌的一种变异型，是一种罕见的甲状腺恶性肿瘤，占甲状腺恶性肿瘤的比例不到1%。我们报告一例57岁女性患者，主诉甲状腺肿大逐渐增大1个半月。细针穿刺提示为髓样癌。血清降钙素水平升高。患者接受了甲状腺全切术及颈部区域淋巴结切除术。组织病理学检查确诊为甲状腺混合性髓样-乳头状癌。由于其预后意义以及为避免任何诊断困境，了解这一实体很重要。