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一种基于网络特征描述的低维方法。

A low dimensional approach on network characterization.

作者信息

Li Benjamin Y S, Zhan Choujun, Yeung Lam F, Ko King T, Yang Genke

机构信息

Department of Electronic Engineering, City University of Hong Kong, Hong Kong, Hong Kong.

Department of Electronic and Information Engineering, The Hong Kong Polytechnic University, Hong Kong, Hong Kong.

出版信息

PLoS One. 2014 Oct 16;9(10):e109383. doi: 10.1371/journal.pone.0109383. eCollection 2014.

DOI:10.1371/journal.pone.0109383
PMID:25329146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4199607/
Abstract

In many applications, one may need to characterize a given network among a large set of base networks, and these networks are large in size and diverse in structure over the search space. In addition, the characterization algorithms are required to have low volatility and with a small circle of uncertainty. For large datasets, these algorithms are computationally intensive and inefficient. However, under the context of network mining, a major concern of some applications is speed. Hence, we are motivated to develop a fast characterization algorithm, which can be used to quickly construct a graph space for analysis purpose. Our approach is to transform a network characterization measure, commonly formulated based on similarity matrices, into simple vector form signatures. We shall show that the [Formula: see text] similarity matrix can be represented by a dyadic product of two N-dimensional signature vectors; thus the network alignment process, which is usually solved as an assignment problem, can be reduced into a simple alignment problem based on separate signature vectors.

摘要

在许多应用中,人们可能需要在大量基础网络中对给定网络进行特征描述,并且这些网络在搜索空间中规模庞大且结构多样。此外,特征描述算法需要具有低波动性和小的不确定性范围。对于大型数据集,这些算法计算量很大且效率低下。然而,在网络挖掘的背景下,一些应用的主要关注点是速度。因此,我们有动力开发一种快速特征描述算法,该算法可用于快速构建用于分析目的的图空间。我们的方法是将通常基于相似性矩阵制定的网络特征描述度量转换为简单的向量形式签名。我们将表明,[公式:见原文]相似性矩阵可以由两个N维签名向量的二元积表示;因此,通常作为分配问题求解的网络对齐过程可以简化为基于单独签名向量的简单对齐问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/51630f7915e9/pone.0109383.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/c056def2d822/pone.0109383.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/f8cdcaee1842/pone.0109383.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/e934ba79a578/pone.0109383.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/c48c11421844/pone.0109383.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/51630f7915e9/pone.0109383.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/c056def2d822/pone.0109383.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/f8cdcaee1842/pone.0109383.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/e934ba79a578/pone.0109383.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/c48c11421844/pone.0109383.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a6a/4199607/51630f7915e9/pone.0109383.g005.jpg

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本文引用的文献

1
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2
Graph mining: procedure, application to drug discovery and recent advances.图挖掘:程序、在药物发现中的应用和最新进展。
Drug Discov Today. 2013 Jan;18(1-2):50-7. doi: 10.1016/j.drudis.2012.07.016. Epub 2012 Aug 5.
3
GraphCrunch 2: Software tool for network modeling, alignment and clustering.GraphCrunch 2:网络建模、对齐和聚类的软件工具。
BMC Bioinformatics. 2011 Jan 19;12:24. doi: 10.1186/1471-2105-12-24.
4
How threshold behaviour affects the use of subgraphs for network comparison.阈行为如何影响子图在网络比较中的应用。
Bioinformatics. 2010 Sep 15;26(18):i611-7. doi: 10.1093/bioinformatics/btq386.
5
Optimal network alignment with graphlet degree vectors.基于图let度向量的最优网络对齐
Cancer Inform. 2010 Jun 30;9:121-37. doi: 10.4137/cin.s4744.
6
Evolutionarily conserved herpesviral protein interaction networks.进化上保守的疱疹病毒蛋白相互作用网络。
PLoS Pathog. 2009 Sep;5(9):e1000570. doi: 10.1371/journal.ppat.1000570. Epub 2009 Sep 4.
7
Uncovering biological network function via graphlet degree signatures.通过图let度特征揭示生物网络功能
Cancer Inform. 2008;6:257-73. Epub 2008 Apr 14.
8
Global alignment of multiple protein interaction networks with application to functional orthology detection.多个蛋白质相互作用网络的全局比对及其在功能直系同源检测中的应用。
Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12763-8. doi: 10.1073/pnas.0806627105. Epub 2008 Aug 25.
9
Alignment of molecular networks by integer quadratic programming.通过整数二次规划实现分子网络比对
Bioinformatics. 2007 Jul 1;23(13):1631-9. doi: 10.1093/bioinformatics/btm156. Epub 2007 Apr 27.
10
Biological network comparison using graphlet degree distribution.使用图let度分布进行生物网络比较。
Bioinformatics. 2007 Jan 15;23(2):e177-83. doi: 10.1093/bioinformatics/btl301.