Wang Tianheng, Brewer Molly, Zhu Quing
Department of Electrical and Computer Engineering, University of Connecticut, Storrs, CT, USA.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Jan-Feb;7(1):1-16. doi: 10.1002/wnan.1306. Epub 2014 Oct 20.
Ovarian cancer has the lowest survival rate among all the gynecologic cancers because it is predominantly diagnosed at late stages due to the lack of reliable symptoms and efficacious screening techniques. Optical coherence tomography (OCT) is an emerging technique that provides high-resolution images of biological tissue in real time, and demonstrates great potential for imaging of ovarian tissue. In this article, we review OCT studies for visualization and diagnosis of human ovaries as well as quantitative extraction of ovarian tissue optical properties for classifying normal and malignant ovaries. OCT combined with other imaging modalities to further improve ovarian tissue diagnosis is also reviewed.
在所有妇科癌症中,卵巢癌的生存率最低,因为由于缺乏可靠的症状和有效的筛查技术,它主要在晚期才被诊断出来。光学相干断层扫描(OCT)是一种新兴技术,可实时提供生物组织的高分辨率图像,并在卵巢组织成像方面显示出巨大潜力。在本文中,我们综述了用于人类卵巢可视化和诊断的OCT研究,以及用于区分正常和恶性卵巢的卵巢组织光学特性的定量提取。还综述了OCT与其他成像方式相结合以进一步改善卵巢组织诊断的情况。