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药物创新:对支出和结果的影响以及药物政策随后面临的挑战,特别提及希腊

Pharmaceutical innovation: impact on expenditure and outcomes and subsequent challenges for pharmaceutical policy, with a special reference to Greece.

作者信息

Karampli E, Souliotis K, Polyzos N, Kyriopoulos J, Chatzaki E

机构信息

Department of Health Economics, National School of Public Health, Athens, Greece ; Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Faculty of Social Sciences, University of Peloponnese, Corinth, Greece.

出版信息

Hippokratia. 2014 Apr;18(2):100-6.

PMID:25336869
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4201392/
Abstract

Over the recent decades, advances in healthcare technology have led to significant improvements in the quality of healthcare and in population health. At the same time, technological change in healthcare, rising national income and expansion of insurance coverage have been acknowledged as the main determinants of the historical growth in health spending in industrialized countries. The pharmaceutical sector is of particular interest as it constitutes a market characterized by rapid technological change and high expenditure growth rates. The purpose of this article is to provide an overview of research findings on the impact of pharmaceutical innovation on pharmaceutical expenditure growth, total health expenditure and population health outcomes and to bring forward the challenges that arise for pharmaceutical policy in Greece.

摘要

在最近几十年里,医疗技术的进步已使医疗保健质量和人口健康状况得到显著改善。与此同时,医疗保健领域的技术变革、国民收入的增长以及保险覆盖范围的扩大,已被公认为工业化国家医疗支出历史增长的主要决定因素。制药行业尤其引人关注,因为它构成了一个以技术变革迅速和支出增长率高为特征的市场。本文旨在概述有关药物创新对药品支出增长、总体医疗支出和人口健康结果影响的研究发现,并提出希腊制药政策面临的挑战。

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本文引用的文献

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Increasing Anti-Infective Drug Expenditure in Tianjin, China: A Decomposition Analysis.中国天津抗感染药物支出增加:一项分解分析
Value Health Reg Issues. 2013 May;2(1):37-42. doi: 10.1016/j.vhri.2013.01.002. Epub 2013 Mar 7.
2
The slowdown in health care spending in 2009-11 reflected factors other than the weak economy and thus may persist.2009-11 年医疗保健支出的放缓反映了除经济疲软以外的因素,因此可能会持续下去。
Health Aff (Millwood). 2013 May;32(5):835-40. doi: 10.1377/hlthaff.2012.1297.
3
Reforms in the Greek pharmaceutical market during the financial crisis.希腊金融危机期间的医药市场改革。
Health Policy. 2013 Jan;109(1):1-6. doi: 10.1016/j.healthpol.2012.08.016. Epub 2012 Sep 7.
4
The impact of new (orphan) drug approvals on premature mortality from rare diseases in the United States and France, 1999-2007.1999-2007 年美国和法国新(孤儿)药批准对罕见病患者过早死亡率的影响。
Eur J Health Econ. 2013 Feb;14(1):41-56. doi: 10.1007/s10198-011-0349-4. Epub 2011 Sep 28.
5
Impact of new drugs and biologics on colorectal cancer treatment and costs.新型药物和生物制剂对结直肠癌治疗和费用的影响。
J Oncol Pract. 2011 May;7(3 Suppl):e30s-7s. doi: 10.1200/JOP.2011.000302.
6
Toward a definition of pharmaceutical innovation.迈向药物创新的定义。
Open Med. 2008;2(1):e4-7. Epub 2008 Jan 30.
7
New drugs and the growth of health expenditure: evidence from diabetic patients in Taiwan.新药与医疗支出的增长:以台湾地区糖尿病患者为例。
Health Econ. 2012 May;21(5):496-513. doi: 10.1002/hec.1724. Epub 2011 Mar 10.
8
The impotence of price controls: failed attempts to constrain pharmaceutical expenditures in Greece.价格管制的无效性:希腊控制药品支出的失败尝试。
Health Policy. 2011 Jul;101(2):162-71. doi: 10.1016/j.healthpol.2010.08.023. Epub 2010 Sep 29.
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Long-term trends in use of and expenditures for cardiovascular medications in Canada.加拿大心血管药物使用情况及支出的长期趋势。
CMAJ. 2009 Jul 7;181(1-2):E19-28. doi: 10.1503/cmaj.081913.
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The effect of Medicare Part D on drug and medical spending.医疗保险处方药计划(Medicare Part D)对药品和医疗支出的影响。
N Engl J Med. 2009 Jul 2;361(1):52-61. doi: 10.1056/NEJMsa0807998.