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一种检测帕金森病患者冻结步态的实用方法。

A practical method for the detection of freezing of gait in patients with Parkinson's disease.

作者信息

Kwon Yuri, Park Sang Hoon, Kim Ji-Won, Ho Yeji, Jeon Hyeong-Min, Bang Min-Jung, Jung Gu-In, Lee Seon-Min, Eom Gwang-Moon, Koh Seong-Beom, Lee Jeong-Whan, Jeon Heung Seok

机构信息

Biomedical Engineering, Konkuk University, Chungju, Korea.

Department of Neurology, Korea University College of Medicine, Seoul, Korea.

出版信息

Clin Interv Aging. 2014 Oct 8;9:1709-19. doi: 10.2147/CIA.S69773. eCollection 2014.

DOI:10.2147/CIA.S69773
PMID:25336936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4199977/
Abstract

PURPOSE

Freezing of gait (FOG), increasing the fall risk and limiting the quality of life, is common at the advanced stage of Parkinson's disease, typically in old ages. A simple and unobtrusive FOG detection system with a small calculation load would make a fast presentation of on-demand cueing possible. The purpose of this study was to find a practical FOG detection system.

PATIENTS AND METHODS

A sole-mounted sensor system was developed for an unobtrusive measurement of acceleration during gait. Twenty patients with Parkinson's disease participated in this study. A simple and fast time-domain method for the FOG detection was suggested and compared with the conventional frequency-domain method. The parameters used in the FOG detection were optimized for each patient.

RESULTS

The calculation load was 1,154 times less in the time-domain method than the conventional method, and the FOG detection performance was comparable between the two domains (P=0.79) and depended on the window length (P<0.01) and dimension of sensor information (P=0.03).

CONCLUSION

A minimally constraining sole-mounted sensor system was developed, and the suggested time-domain method showed comparable FOG detection performance to that of the conventional frequency-domain method. Three-dimensional sensor information and 3-4-second window length were desirable. The suggested system is expected to have more practical clinical applications.

摘要

目的

冻结步态（FOG）在帕金森病晚期常见，尤其在老年患者中，会增加跌倒风险并影响生活质量。一个简单且不引人注意、计算负荷小的FOG检测系统能够实现按需提示的快速呈现。本研究的目的是找到一种实用的FOG检测系统。

患者与方法

开发了一种安装在鞋底的传感器系统，用于在步态期间进行不引人注意的加速度测量。20名帕金森病患者参与了本研究。提出了一种简单快速的时域FOG检测方法，并与传统的频域方法进行比较。针对每位患者对FOG检测中使用的参数进行了优化。

结果

时域方法的计算负荷比传统方法少1154倍，且两个域之间的FOG检测性能相当（P = 0.79），并取决于窗口长度（P < 0.01）和传感器信息维度（P = 0.03）。

结论

开发了一种限制最小的鞋底安装传感器系统，所提出的时域方法显示出与传统频域方法相当的FOG检测性能。三维传感器信息和3 - 4秒的窗口长度较为理想。所提出的系统有望具有更多实际临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/7c21e277b534/cia-9-1709Fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a7501d6f2a3c/cia-9-1709Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a21334573a91/cia-9-1709Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/e7d8a6e74210/cia-9-1709Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/84966b30848f/cia-9-1709Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a7371df9587b/cia-9-1709Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/08330f9f9cee/cia-9-1709Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/7c21e277b534/cia-9-1709Fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a7501d6f2a3c/cia-9-1709Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a21334573a91/cia-9-1709Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/e7d8a6e74210/cia-9-1709Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/84966b30848f/cia-9-1709Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/a7371df9587b/cia-9-1709Fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/08330f9f9cee/cia-9-1709Fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/242a/4199977/7c21e277b534/cia-9-1709Fig7.jpg

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