CATH：基因组序列的全面结构和功能注释。
CATH: comprehensive structural and functional annotations for genome sequences.
作者信息
Sillitoe Ian, Lewis Tony E, Cuff Alison, Das Sayoni, Ashford Paul, Dawson Natalie L, Furnham Nicholas, Laskowski Roman A, Lee David, Lees Jonathan G, Lehtinen Sonja, Studer Romain A, Thornton Janet, Orengo Christine A
机构信息
Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK
Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
出版信息
Nucleic Acids Res. 2015 Jan;43(Database issue):D376-81. doi: 10.1093/nar/gku947. Epub 2014 Oct 27.
The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235,000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.
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