Protein Data Bank in Europe, European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Res. 2014 Jan;42(Database issue):D285-91. doi: 10.1093/nar/gkt1180. Epub 2013 Nov 27.
The Protein Data Bank in Europe (pdbe.org) is a founding member of the Worldwide PDB consortium (wwPDB; wwpdb.org) and as such is actively engaged in the deposition, annotation, remediation and dissemination of macromolecular structure data through the single global archive for such data, the PDB. Similarly, PDBe is a member of the EMDataBank organisation (emdatabank.org), which manages the EMDB archive for electron microscopy data. PDBe also develops tools that help the biomedical science community to make effective use of the data in the PDB and EMDB for their research. Here we describe new or improved services, including updated SIFTS mappings to other bioinformatics resources, a new browser for the PDB archive based on Gene Ontology (GO) annotation, updates to the analysis of Nuclear Magnetic Resonance-derived structures, redesigned search and browse interfaces, and new or updated visualisation and validation tools for EMDB entries.
欧洲生物分子结构数据库(PDBe,pdbe.org)是全球蛋白质数据库合作组织(wwPDB,wwpdb.org)的创始成员之一,因此积极参与通过单一的全球大分子结构数据档案 PDB 进行大分子结构数据的存储、注释、修正和传播。同样,PDBe 也是电子显微镜数据的 EMDataBank 组织(emdatabank.org)的成员,该组织管理着用于电子显微镜数据的 EMDB 档案。PDBe 还开发了一些工具,帮助生物医学科学界有效利用 PDB 和 EMDB 中的数据进行研究。在这里,我们描述了新的或改进的服务,包括更新了到其他生物信息学资源的 SIFTS 映射、基于基因本体(GO)注释的 PDB 档案新浏览器、对基于核磁共振衍生结构的分析更新、重新设计的搜索和浏览界面,以及 EMDB 条目的新的或更新的可视化和验证工具。