Xiaoli Yang, Chao Jiang, Wen Pan, Wenming Xu, Fang Liang, Ning Li, Huijuan Mu, Jun Na, Ming Lv, Xiaoxia An, Chuanyou Yu, Zenguo Fu, Lili Li, Lianzheng Yu, Lijuan Tong, Guowei Pan
Institute of Chronic Disease, Liaoning Provincial Center for Disease Control and Prevention, Shenyang city, China.
Department of Psychiatry, Dalian Medical University, Dalian city, China.
PLoS One. 2014 Oct 31;9(10):e111223. doi: 10.1371/journal.pone.0111223. eCollection 2014.
To describe the prevalence of DSM-IV disorders and comorbidity in a large school-based sample of 6-17 year old children and adolescents in northeast China.
A two-phase cross-sectional study was conducted on 9,806 children. During the screening phase, 8848 children (90.23%) and their mothers and teachers were interviewed using the Strengths and Difficulties Questionnaire (SDQ). During the diagnostic phase, 1129 children with a positive SDQ and 804 randomly selected children with a negative SDQ (11%), and their mothers and teachers, were interviewed using the Development and Well-Being Assessment (DAWBA).
The overall prevalence of DSM-IV disorders was 9.49% (95% CI = 8.10-11.10%). Anxiety disorders were the most common (6.06%, 95% CI = 4.92-7.40), followed by depression (1.32%, 95% CI = 0.91-1.92%), oppositional defiant disorder (1.21%, 95%CI = 0.77-1.87) and attention-deficit hyperactivity disorder (0.84%, 95% CI = 0.52-1.36%). Of the 805 children with a psychiatric disorder, 15.2% had two or more comorbid disorders.
Approximately one in ten Chinese school children has psychiatric disorders involving a level of distress or social impairment likely to warrant treatment. Prevention, early identification and treatment of these disorders are urgently needed and pose a serious challenge in China.
描述中国东北地区6至17岁儿童和青少年大型校本样本中《精神疾病诊断与统计手册》第四版(DSM-IV)所定义疾病的患病率及共病情况。
对9806名儿童进行了两阶段横断面研究。在筛查阶段,使用长处与困难问卷(SDQ)对8848名儿童(90.23%)及其母亲和教师进行了访谈。在诊断阶段,使用发育与幸福感评估(DAWBA)对1129名SDQ筛查呈阳性的儿童以及804名随机抽取的SDQ筛查呈阴性的儿童(11%)及其母亲和教师进行了访谈。
DSM-IV所定义疾病的总体患病率为9.49%(95%置信区间=8.10-11.10%)。焦虑症最为常见(6.06%,95%置信区间=4.92-7.40),其次是抑郁症(1.32%,95%置信区间=0.91-1.92%)、对立违抗性障碍(1.21%,95%置信区间=0.77-1.87)和注意力缺陷多动障碍(0.84%,95%置信区间=0.52-1.36%)。在805名患有精神疾病的儿童中,15.2%患有两种或更多的共病。
大约十分之一的中国在校儿童患有精神疾病,其痛苦程度或社会功能损害程度可能需要治疗。在中国,迫切需要对这些疾病进行预防、早期识别和治疗,这构成了一项严峻挑战。