Bazargan Maedeh, Dehghani Akram, Ramezani Mohammad Arash, Ramezani Alireza
Department of Psychology, Najafabad Branch Islamic Azad University Najafabad Iran.
Behsa Clinic Tehran Iran.
Health Sci Rep. 2023 Oct 2;6(10):e1584. doi: 10.1002/hsr2.1584. eCollection 2023 Oct.
One of the most common mental disorders among children and adolescent is depression. Some of the conducted studies indicate a too-high prevalence of depression, which cannot be generalized to the entire country. So the pooled estimation of the results of different studies is very important to reach valid results. So the current study aimed to determine the prevalence of depression among Iranian children and adolescents using an updated systematic review and meta-analysis.
A random-effects model was used to estimate the pooled prevalence of depression ( = 99.7% and Cochran's , < 0.001). To assess the effect of different factors on heterogeneity, the univariate meta-regression model was used. Publication bias was evaluated by Beggs and Eggers tests as well as funnel plots. Data were analyzed by STATA v 11 (StataCorp.). The significance level of the tests was considered less than 0.05.
The prevalence of depression was 33.3% (95% CI: 27.3-39.2). The most prevalence estimated using the Beak questionnaire (57.1% [95% CI: 50.2-64.0]) and the lowest was estimated using the K-SADS-PL (9.0% [95% CI: 4.0-13.6]). This estimate among females was more than among males (47.2% [95% CI: 35.4-58.9] vs. 30.5 [95% CI: 7.4-53.6]). Regarding the geographical region, the most and the lowest amount of depression was seen in the central with 41.7% (95% CI: 19.2-64.3) and southern region with 21.9% (95% CI: 14.2-29.6), respectively.
The high prevalence of depressive disorders in Iranian children emphasizes the importance of prevention measures for these disorders.
儿童和青少年中最常见的精神障碍之一是抑郁症。一些已开展的研究表明抑郁症患病率过高，但这不能推广至整个国家。因此，汇总不同研究结果进行估计对于获得有效结果非常重要。所以，本研究旨在通过更新的系统评价和荟萃分析来确定伊朗儿童和青少年中抑郁症的患病率。
采用随机效应模型估计抑郁症的合并患病率（ = 99.7%， Cochr an's ， < 0.001）。为评估不同因素对异质性的影响，使用单变量元回归模型。通过Beggs检验和Eggers检验以及漏斗图评估发表偏倚。数据采用STATA v 11（StataCorp.）进行分析。检验的显著性水平设定为小于0.05。
抑郁症患病率为33.3%（95%置信区间：27.3 - 39.2）。使用Beak问卷估计的患病率最高（57.1% [95%置信区间：50.2 - 64.0]），使用K - SADS - PL估计的患病率最低（9.0% [95%置信区间：4.0 - 13.6]）。女性的这一估计患病率高于男性（47.2% [95%置信区间：35.4 - 58.9] 对 30.5 [95%置信区间：7.4 - 53.6]）。关于地理区域，抑郁症患病率最高和最低的分别是中部地区，为41.7%（95%置信区间：19.2 - 64.3）和南部地区，为21.9%（95%置信区间：14.2 - 29.6）。
伊朗儿童中抑郁症的高患病率凸显了针对这些疾病采取预防措施的重要性。
