Limkittikul Kriengsak, Brett Jeremy, L'Azou Maïna
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
sanofi-aventis Singapore Pte Ltd, Singapore.
PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3241. doi: 10.1371/journal.pntd.0003241. eCollection 2014.
A literature survey and analysis was conducted to describe the epidemiology of dengue disease in Thailand reported between 2000 and 2011. The literature search identified 610 relevant sources, 40 of which fulfilled the inclusion criteria defined in the review protocol. Peaks in the number of cases occurred during the review period in 2001, 2002, 2008 and 2010. A shift in age group predominance towards older ages continued through the review period. Disease incidence and deaths remained highest in children aged ≤ 15 years and case fatality rates were highest in young children. Heterogeneous geographical patterns were observed with higher incidence rates reported in the Southern region and serotype distribution varied in time and place. Gaps identified in epidemiological knowledge regarding dengue disease in Thailand provide several avenues for future research, in particular studies of seroprevalence.
PROSPERO CRD42012002170.
进行了一项文献调查与分析，以描述2000年至2011年期间泰国登革热疾病的流行病学情况。文献检索确定了610个相关来源，其中40个符合综述方案中定义的纳入标准。在2001年、2002年、2008年和2010年的审查期间出现了病例数高峰。在整个审查期间，年龄组优势向老年人群体转移的趋势持续存在。≤15岁儿童的疾病发病率和死亡率仍然最高，幼儿的病死率最高。观察到不同的地理模式，南部地区报告的发病率较高，血清型分布随时间和地点而变化。泰国登革热疾病流行病学知识方面存在的差距为未来研究提供了多条途径，特别是血清流行率研究。
PROSPERO CRD42012002170。
