Mohd-Zaki Abdul Hamid, Brett Jeremy, Ismail Ellyana, L'Azou Maïna
Vector Borne Disease Sector, Ministry of Health Malaysia, Kuala Lumpur, Malaysia.
Sanofi Pasteur, Singapore Pte. Ltd., Singapore.
PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3159. doi: 10.1371/journal.pntd.0003159. eCollection 2014.
A literature survey and analysis was conducted to describe the epidemiology of dengue disease in Malaysia between 2000 and 2012. Published literature was searched for epidemiological studies of dengue disease, using specific search strategies for each electronic database; 237 relevant data sources were identified, 28 of which fulfilled the inclusion criteria. The epidemiology of dengue disease in Malaysia was characterized by a non-linear increase in the number of reported cases from 7,103 in 2000 to 46,171 in 2010, and a shift in the age range predominance from children toward adults. The overall increase in dengue disease was accompanied by a rise in the number, but not the proportion, of severe cases. The dominant circulating dengue virus serotypes changed continually over the decade and differed between states. Several gaps in epidemiological knowledge were identified; in particular, studies of regional differences, age-stratified seroprevalence, and hospital admissions.
PROSPERO #CRD42012002293.
进行了一项文献调查与分析，以描述2000年至2012年马来西亚登革热疾病的流行病学情况。利用针对每个电子数据库的特定检索策略，在已发表文献中检索登革热疾病的流行病学研究；共识别出237个相关数据源，其中28个符合纳入标准。马来西亚登革热疾病的流行病学特征为报告病例数呈非线性增长，从2000年的7103例增至2010年的46171例，且年龄优势范围从儿童转向成人。登革热疾病的总体增加伴随着重症病例数量的上升，但比例未变。在这十年间，主要流行的登革热病毒血清型不断变化，且各州之间存在差异。发现了流行病学知识方面的若干空白；特别是区域差异、年龄分层血清阳性率以及住院情况的研究。
PROSPERO #CRD42012002293
