Al-Hashmi Khamis M, Al-Abri Mohammed A, Al-Zakwani Ibrahim S, Al-Waili Khalid A, Al-Rasadi Khalid H, Al-Sabti Hilal A, Hassan Mohammed O
Department of Physiology and Clinical Physiology, College of Medicine and Health Sciences, Sultan Qaboos University, PO Box 35, Postal Code 123, AlKhoud, Muscat, Sultanate of Oman. Fax. +968 24143514. E-mail.
Saudi Med J. 2014 Nov;35(11):1367-72.
To determine the reference values of arterial stiffness indices, particularly augmentation index (AIx) and pulse wave velocity (PWV) using applanation tonometry in a healthy Omani Arab population.
This prospective study was carried out in the Department of Clinical Physiology, Sultan Qaboos University Hospital, Muscat, Oman over a 2-year period from June 2011 to June 2013. The central AIx, aortic PWV (AoPWV), and central pulse pressure (CPP) were recorded from 120 healthy subjects recruited randomly from a normal population using a SphygmoCor device. The 2.5th and 97.5th percentiles were used to determine the reference ranges for men and women separately. Analyses were performed using univariate statistics.
The mean age of the cohort was 38 years for men, and 35 years for women, with the ages ranging from 20-53 years. The overall mean central AIx was 13±11%, and for AoPWV was 6.7±1.6 m/s. The central AIx was higher in women (17 versus 10%; p<0.001), whereas the AoPWV was higher in men (7.1 versus 6.3 m/s; p=0.003). Subjects were categorized according to the gender and age decade, and reference values for CPP, central AIx, and AoPWV were obtained.
This study reports the reference values for arterial stiffness indices from an Omani Arab population; the results of which should be interpreted in the context of its limitations.
使用压平式眼压计测定阿曼阿拉伯健康人群的动脉僵硬度指标，特别是增强指数（AIx）和脉搏波速度（PWV）的参考值。
这项前瞻性研究于2011年6月至2013年6月在阿曼马斯喀特苏丹卡布斯大学医院临床生理科进行，为期2年。使用SphygmoCor设备从正常人群中随机招募120名健康受试者，记录其中心AIx、主动脉PWV（AoPWV）和中心脉压（CPP）。分别使用第2.5百分位数和第97.5百分位数来确定男性和女性的参考范围。采用单变量统计进行分析。
该队列男性的平均年龄为38岁，女性为35岁，年龄范围为20 - 53岁。总体中心AIx平均为13±11%，AoPWV平均为6.7±1.6 m/s。女性的中心AIx较高（17%对10%；p<0.001），而男性的AoPWV较高（7.1 m/s对6.3 m/s；p = 0.003）。根据性别和年龄十年对受试者进行分类，并获得了CPP、中心AIx和AoPWV的参考值。
本研究报告了阿曼阿拉伯人群动脉僵硬度指标的参考值；其结果应在其局限性的背景下进行解释。
