Larson T V
Department of Civil Engineering, University of Washington, Seattle 98195.
Environ Health Perspect. 1989 Feb;79:7-13. doi: 10.1289/ehp.89797.
The effects of ambient relative humidity and particle size on acid deposition within the airways have been examined with a computer model. For H2SO4 particles initially at 90% relative humidity in ambient air that are inhaled via the nose or mouth, there is significant deposition of acid in the airways even in the presence of typical values of respiratory NH3. When these same particles are found in a fog at 100.015% relative humidity, there is significant deposition of acid in the nasal region during nose breathing but insignificant deposition to the deep lung for either nose or mouth breathing. The factors governing the partitioning of labile acid gases in the gas and liquid phases prior to inhalation are also discussed.
已使用计算机模型研究了环境相对湿度和颗粒大小对气道内酸沉积的影响。对于最初在环境空气中相对湿度为90%的硫酸颗粒，通过鼻子或嘴巴吸入时，即使在呼吸道氨的典型值存在的情况下，气道中也会有大量酸沉积。当这些相同的颗粒存在于相对湿度为100.015%的雾中时，经鼻呼吸时鼻腔区域会有大量酸沉积，但无论是经鼻还是经口呼吸，酸向深部肺部的沉积都不显著。还讨论了吸入前控制不稳定酸性气体在气相和液相中分配的因素。
