Chaudhari Ramesh R, Dahiya M S
Institute of Forensic Sciences, Gujarat Forensic Sciences University, Gandhinagar, Gujarat, India.
Indian J Hum Genet. 2014 Apr;20(2):148-52. doi: 10.4103/0971-6866.142879.
The genetic diversity and forensic parameters based on 15 autosomal short tandem repeats (STR) loci; D8S1179,D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317,D16S539, D2S1338, D19S433, vWA, TPOX, D18S51,D5S818, and FGA in AmpFLSTR® Identifiler™ kit from Applied Biosystems, Foster City, CA, USA were evaluated in saliva samples of 297 unrelated individuals from the Bhil Tribe population of Gujarat state, India to study genetic diversities and relatedness of this population with other national and international populations.
Statistical analysis of the data revealed all loci were within Hardy-Weinberg Equilibrium expectations with the exception of the locus vWA (0.019) and locus D18S51 (0.016). The neighbour joining phylogeny tree and Principal Co-ordinate Analysis plot constructed based on Fst distances from autosomal STRs allele frequencies of the present study and other national as well as international populations show clustering of all the South Asian populations in one branch of the tree, while Middle Eastern and African populations cluster in a separate branch.
Our findings reveal strong genetic affinities seen between the Indo-European (IE) speaking Bhil Tribe of Gujarat and Dravidian groups of South India.
基于15个常染色体短串联重复序列（STR）位点；即美国加利福尼亚州福斯特城应用生物系统公司的AmpFLSTR® Identifiler™试剂盒中的D8S1179、D21S11、D7S820、CSF1PO、D3S1358、TH01、D13S317、D16S539、D2S1338、D19S433、vWA、TPOX、D18S51、D5S818和FGA，对来自印度古吉拉特邦比尔部落群体的297名无关个体的唾液样本进行评估，以研究该群体与其他国家和国际群体的遗传多样性和相关性。
数据的统计分析表明，除vWA位点（0.019）和D18S51位点（0.016）外，所有位点均符合哈迪-温伯格平衡预期。基于本研究以及其他国家和国际群体的常染色体STR等位基因频率的Fst距离构建的邻接法系统发育树和主坐标分析图显示，所有南亚群体聚集在树的一个分支中，而中东和非洲群体聚集在另一个分支中。
我们的研究结果揭示了古吉拉特邦说印欧语（IE）的比尔部落与南印度达罗毗荼群体之间存在很强的遗传亲和力。
