首例由马提尼克利什曼原虫引起的内脏利什曼病。

First case of visceral leishmaniasis caused by Leishmania martiniquensis.

作者信息

Liautaud Bernard, Vignier Nicolas, Miossec Charline, Plumelle Yves, Kone Moumini, Delta Delphine, Ravel Christophe, Cabié André, Desbois Nicole

机构信息

Department of Tropical and Infectious Disease, University Hospital of Fort-de-France, Fort-de-France, Martinique, French West Indies; Department of Tropical and Infectious Disease, University Hospital of Avicenne, Bobigny, France; Parasitology and Mycology Laboratory, University Hospital of Fort-de-France, Fort-de-France, Martinique, French West Indies; Hematology Laboratory, University Hospital of Fort-de-France, Fort-de-France, Martinique, French West Indies; Hematology Unit, University Hospital of Fort-de-France, Fort-de-France, Martinique, French West Indies; University Hospital of Montpellier, Unité Mixte de Recherche 5290, French National Reference Center for Leishmaniasis, Montpellier, France; Faculté des Antilles et de la Guyane, Institut National de la Santé et de la Recherche Medicale CIC1424 and EA4537, Martinique, French West Indies.

出版信息

Am J Trop Med Hyg. 2015 Feb;92(2):317-9. doi: 10.4269/ajtmh.14-0205. Epub 2014 Nov 17.

DOI:10.4269/ajtmh.14-0205

PMID:25404076

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4347334/

Abstract

We report the first case of visceral leishmaniasis (VL) caused by Leishmania martiniquensis in the Caribbean, which until now, was known only to cause cutaneous leishmaniasis. The disease presented with fatigue, anemia, and hepatosplenomegaly in a 61-year-old man with human immunodeficiency virus (HIV) infection who was receiving antiretroviral therapy. Diagnosis was made by bone marrow biopsy. VL is life-threatening, and its emergence in the Caribbean is of concern.

摘要

我们报告了加勒比地区首例由马提尼克利什曼原虫引起的内脏利什曼病（VL），此前已知该寄生虫仅会引发皮肤利什曼病。一名61岁的人类免疫缺陷病毒（HIV）感染者在接受抗逆转录病毒治疗期间，出现了疲劳、贫血和肝脾肿大等症状，被诊断为此病。诊断是通过骨髓活检做出的。内脏利什曼病会危及生命，其在加勒比地区的出现令人担忧。

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