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亚洲人群中获得性免疫缺陷综合征患者巨细胞病毒性视网膜炎相关视网膜脱离手术的结果

Outcomes of cytomegalovirus retinitis-related retinal detachment surgery in acquired immunodeficiency syndrome patients in an Asian population.

作者信息

Wong John X, Wong Elizabeth P, Teoh Stephen C

机构信息

Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore.

出版信息

BMC Ophthalmol. 2014 Nov 27;14:150. doi: 10.1186/1471-2415-14-150.

DOI:10.1186/1471-2415-14-150
PMID:25429876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4280744/
Abstract

BACKGROUND

This study reports the surgical outcomes of acquired immunodeficiency syndrome (AIDS) patients with Cytomegalovirus retinitis (CMVR) -related retinal detachments(RD) in an Asian population.

METHODS

Review of CMVR characteristics, surgical outcomes and complications in 19 eyes with CMVR-related RD that underwent surgery from January 2000 to June 2011.

RESULTS

CMVR was inactive in 73.7% of the eyes at time of surgery. Anatomical success was achieved in 14 eyes. Seven eyes (36.8%) had improvement of two or more lines in visual acuity (VA) and 8 eyes (42.1%) maintained VA. Thirteen eyes presented with worse than 6/120 vision, with 30.8% of them achieving ambulatory vision or better. Five eyes had re-detachments. Median durations from CMVR and immune recovery uveitis (IRU) diagnoses to RD were 2.7 and 1.0 months respectively.

CONCLUSIONS

Surgery for CMVR-related RD is associated with good anatomical outcomes with most eyes maintaining or having improved vision. CMVR lesion size of <50% retinal area is associated with better outcomes. Eyes with CMVR and IRU require close monitoring for RD.

摘要

背景

本研究报告了亚洲人群中获得性免疫缺陷综合征（AIDS）合并巨细胞病毒性视网膜炎（CMVR）相关视网膜脱离（RD）患者的手术结果。

方法

回顾2000年1月至2011年6月期间接受手术的19只患有CMVR相关RD眼睛的CMVR特征、手术结果及并发症。

结果

手术时73.7%的眼睛CMVR处于静止状态。14只眼睛获得解剖学成功。7只眼睛（36.8%）视力（VA）提高两行或更多，8只眼睛（42.1%）视力维持稳定。13只眼睛视力低于6/120，其中30.8%达到可走动视力或更好。5只眼睛再次发生视网膜脱离。从CMVR诊断到RD以及从免疫恢复性葡萄膜炎（IRU）诊断到RD的中位持续时间分别为2.7个月和1.0个月。

结论

CMVR相关RD的手术具有良好的解剖学结果，大多数眼睛视力维持或提高。CMVR病变面积<50%视网膜区域的眼睛预后较好。患有CMVR和IRU的眼睛需要密切监测RD情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/3e7428c4ce9d/12886_2014_520_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/5e9b84041581/12886_2014_520_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/79d9486dfe6a/12886_2014_520_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/3e7428c4ce9d/12886_2014_520_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/5e9b84041581/12886_2014_520_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/79d9486dfe6a/12886_2014_520_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ac0/4280744/3e7428c4ce9d/12886_2014_520_Fig3_HTML.jpg

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